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ImmunoepigeneticsXXI. Methylation patterns of CpG vs histone modification of specific loci must be sequenced to verify pathophysiological events. DJGPhD. 22.1.23 Authentic Biochemistry.
References
Hum Genomics. 2021; 15: 24
JCI Insight. 2020 Sep 3;5(17):e138443
Nature Reviews Genetics volume 14, pages 204–220 (2013)
3 years, 9 months ago
A Special Message for Authentic Biochemists. A direct way to contact your host and a little more. DJGPhD.21.1.23 Authentic Biochemistry Productions.
Rather than referencing this episode I am enlisting your input.
Please email me at our new email address:
authenticbiochemistry@gmail.com
Sincerely…
3 years, 9 months ago
Immunoepigenetics XX. Inflammatory cytokines and associated transcription factors are controlled by epigenetically regulated microRNA. DJGPhD.20.1.23. Authentic Biochemistry.
References
Dr Guerra's micro RNA lectures
FEBS J Volume278, Issue10 May 2011. Pages 1598-1609
International Journal of Molecular Sciences 2013. 14(11…
3 years, 9 months ago
ImmunoEpigeneticsXIX. Diet-induced and db/db mouse model Type 2 diabetes is dissimilar to the human pathophysiology but shares epigenetic mechanisms controlling pro-inflammatory PLA2/COX2/PGE2.
References
Dr. Guerra's lipid lectures
JCI Insight. 2020 Sep 3;5(17):e138443
Proc Natl Acad Sci U S A. 1998 Mar 31; 95(7): 4061–4065.
3 years, 9 months ago
ImmunoepigeneticsXVIII. Variable DNA and histone methylation in cooperation with micro RNA mediate macrophage plasticity,inflammation and wound repair in T2D patients. DJGPhD.18.1.23.AuthenticBiochem.
Reference
JCI Insight . 2020 Sep 3;5(17):e138443
3 years, 9 months ago
Epistemological integration into realized metaphysicsV. Energy and mass like space and time are estimations of uncertain certainties yet are used as universals in physico-chemical event ontologies
References
Thomas Hobbs-Leviathan
Heraclitus-Collected Works
3 years, 9 months ago
Immunoepigenetics XVII.TGF beta involvement in disease pathology and normal developmental physiology demonstrates the complexity of categorical ontologies in biochemical events.DJGPhD.13.1.23.AB
References
JCI Insight . 2020 Sep 3;5(17):e138443
J Clin Invest. 2022 Apr 15;132(8):e151020
3 years, 9 months ago
ImmunoepigeneticsXVI. TGFbeta 1 and subfamily member Activin A diferentially alter the categorical valence and modality of Th17 cells in multiple sclerosis via receptor kinase modulatory specificity.
References
Immunity. 2021 Feb 9; 54(2): 308–323.e6.
J Endocrinol. 2003 Sep;178(3):479-89.
3 years, 9 months ago
ImmunoepigeneticsXV. In utero fetal exposure to high concentration of maternal cortisol can induce histone code hypomethylation proximal to the TGF B-1 receptor resulting in adult OA.DJGPhD.12Jan23
References
Stem Cell Res Ther. 2021; 12: 163
Biomedicines. 2021 Nov; 9(11): 1666
3 years, 9 months ago
ImmunoepigeneticsXIV. Epithelial cell metabolism and the potential transition to mesenchyma is regulated by TGF-Beta and linked to ALK-1 receptor associated OA. DJGPhD.11Jan23.Authentic Biochemistry.
References
Clin Podiatr Med Surg . 2001 Jan;18(1):35-53
Biomedicines. 2021 Nov; 9(11): 1666
3 years, 9 months ago