Podcast Episodes

Cytoepigenetics XI. The Treg essential linneage specific transcription factor FOXp3 promoter is regionally variably demethylated and acetylated to control Th immunosuppression.DJGPhD.04.Jan.23.

References

Front. Immunol. 2015. 6: 493.

Prostaglandins Leukot Essent Fatty Acids. 2015 Jul;98:49-55

3 years, 9 months ago

Epistemological integration into realized metaphysics III. Mensam de phaenomenus and the concept of evidentiary existentialism in research science. DJGPhD.01Jan23.Authentic Biochemistry.

References

Anaximander 6th century B.C.

Plato-Timaeous 4th century B.C.

Kant 1781 Critique of Pure Reason

Basic quantum physics notes

Dr Guerra Neuro…

3 years, 9 months ago

ImmunoEpigenetics X(A). Inhibtion of histone trimethyl-Lys demethylases as arbiter of controlling human Acute Myeloid Leukaemia (AML). Dr Daniel J. Guerra. 30.12.22. Authentic Biochemistry

References

The Journal of Biological Chemistry16/2/2018293: 2422-2437.

Anal Cell Pathol (Amst). 2018; 2018: 787.1814

Nature Reviews Drug Discovery. S…

3 years, 9 months ago

ImmunoEpigeneticsX. Inhibtion of histone trimethyl-Lys demethylases as arbiter of controlling human Acute Myeloid Leukaemia (AML). Dr Daniel J. Guerra. 30.12.22. Authentic Biochemistry

References

J Cancer Res Clin Oncol. 2018; 144(6): 1065–1077

Nature Reviews Drug Discovery. Sep2014, Vol. 13 Issue 9, p673-691

Anal Cell Pathol (Amst)…

3 years, 9 months ago

Diabetes XXV. Obesity linked disruption of adipose mediated endocrine hormone control over fatty acid turnover from TAG leads to T2D in humans. Dr. Daniel J. Guerra. 3April22.Authentic Biochemistry

References

Dr. Guerra lecture materials

Progress in Lipid Research Volume 74, April 2019, Pages 145-159

3 years, 9 months ago

Holiday Ethanol Abuse Lecture I. EtoH ingestion, while intoxicating redox metabolism is also a membrane lipid -protein interacting agent that corrupts inwardly rectifying K voltage gated channels.

References

Dr Guerra EtOH lectures

PNAS November 5, 2013 vol. 110 no. 45

Alcohol, 2017-12-01, Volume 65, Pages 51-62

3 years, 9 months ago

ImmunoEpigeneticsIX. Promoter/Enhancer proximal and distal epigenetic signatures and transcription factor protein heterogeneity compose gene expression event ontology.DJGPhD.29.12.22.AuthenticBiochem

References

Proc Natl Acad Sci U S A. 2021 Nov 16; 118(46)

Nat Rev Mol Cell Biol. 2021 Dec 1; 22(12): 815–833. 

3 years, 9 months ago

More "mere" epistemology opening a door to metaphysics II. Non-canonical epi-rational and epi-empirical retailoring of understanding and imagination via research scientific endojectification.DJGPhD.

References

Dr. Guerra's ongoing flight into the telos of research science.

3 years, 9 months ago

ImmunoepigeneticsVIII. Protective immunotolerant neonate Th1 inactivity involves IL-12 p35subunit promoter methylation. DJGPhD.23.12.22. Authentic Biochemistry Podcast

References

Trends in Immunology. REVIEW. 2017. VOLUME 38, ISSUE 4, P287-297.

J Biomed Sci. 2014 Aug 19;21(1):76.

3 years, 10 months ago

Holiday Ethanol Use VIII. EtOH induced cAMP /CREB associated PKA kinase driven phosphorylation cascade co-opts the TLR4-mediated neuroinflammatory/neurotoxic CNS-microglial axis.DJGPhD.22.12.22.AB.

References

Neural Plasticity. 2019; 2019: 1648736.

Molecular Pharmacology May 2017, 91 (5) 451-463.

3 years, 10 months ago