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Diabetes XXVIII. Diabetic nephropathy is a consequence of non-esterified free fatty acid associated ceramide induction of the IRS-1 phosphorylation in glomerular podocytes inducing inflammation
References
Dr Guerra lecture notes
Front. Endocrinol., 14 October 2014.
Sci Rep. 2020; 10: 21628.
4 years, 1 month ago
Diabetes XXVII. Dyslipidaemia and the Insulin Resistance Axis. Dr. Daniel J. Guerra. Authentic Biochemistry Podcast 7April2022.
References
Dr. Guerra's lectures
Curr Med Chem. 2017;24(17):1827-1852
Cancer Res. 2018 Apr 1; 78(7): 1713–1725
4 years, 1 month ago
Diabetes XXVI. Adipogenic and hypertrophic adiposity differentially control dyslipidaemia and Insulin resistance in association with pro-inflammatory cytokine induced T2D and breast cancer.DJGPhD.
References
Dr. Guerra's lipid lecture notes
Cancer Res. 2018 Apr 1; 78(7): 1713–1725.
Progress in Lipid Research Volume 74, April 2019, Pages 145-159
4 years, 1 month ago
Diabetes XXIV. Sphingosine 1-phosphate targeting and the abalation of primary breast cancer metastasis: IL6 mediated tumorigenesis blockade? Dr Daniel J. Guerra 01April2022. Authentic Bbiochemistry
References
Dr Guerra's notes
Front. Physiol., 30 January 2019 | https://doi.org/10.3389/fphys.2019.00042
4 years, 1 month ago
Diabetes XXIII. Obesity-associated IL6 and sphingosine 1-phosphate are linked to breast cancer.Dr. Daniel J. Guerra. 31 March 2022. Authentic Biochemstry
References
Dr. Guerra's lecture notes
Front. Physiol., 30 January 2019 | https://doi.org/10.3389/fphys.2019.00042
Cold Spring Harb PerspectBiol. 201…
4 years, 1 month ago
Diabetes XXII. Obesity and cancer are linked by inflammation and dyslipidaemia. Dr Daniel J. Guerra. 30.3.22 Authentic Biochemistry
References
Dr Guerra's lectures notes
Cancer Res. 2018 Apr 1; 78(7): 1713–1725
Cold Spring Harb PerspectBiol. 2018 Feb; 10(2): a028415.
4 years, 1 month ago
Diabetes XXI. TAG accumulation in skeletal muscle of diabetics vs athletes and suggested role of Intramuscular TAG in Insulin Resistance due to subcelluar localization of lipid droplets. DJGPhD.27.3
References
Dr Guerra's lecture notes
Diabetologia. 2021 Jan; 64(1): 168–180
Diabetologia. 2020 Dec;63(12):2654-2664
4 years, 1 month ago
Diabetes XX. Intermediary metabolic allosteric regulation in the Myocardial Infarcted heart reveals HF aetiology from obesity-linked Type 2 Diabetes. DJGPhD.25.3.22. Authentic Biochemistry Production
References
Dr. Guerra lecture notes
J AM Coll Cardiology Basic Trans Science.2019. (4) 3: 385-400
4 years, 1 month ago
Diabetes XIX. THe ketogenesis bioenergetic system can be corrupted via DAG-kinase mediated pyroptosis in the obese/T2D CNS. Dr. Dan Guerra. 22.3.22. Authentic Biochemistry Podcast
References
Dr. Guerra lecture notes
Circulation Research Volume 128, Issue 10, 14 May 2021; Pages 1419-1420
Adv Exp Med Biol . 2017;960:135-160.
Curr…
4 years, 2 months ago
Diabetes XVIII. Myokine mediated muscle mass signaling is corrupted by obesity linked Type 2 diabetes via massive inflammation and dyslipidaemia.DJGPhD. 21.3.22. Authentic Biochemistry
References
Dr. Guerra's lecture notes
J Immunol. 2018 Nov 15;201(10):2934-2946
Endocr Rev. 2020 Aug; 41(4): 594–609.
4 years, 2 months ago