Podcast Episodes

CytoEpigenetics XIX. Some examples of epigenetic methylation and acetylation patterns in disease and the concept of maintenance methylation. Dr Daniel J. Guerra. 06June2022

References

Dr Guerra's notes

Arteriosclerosis, Thrombosis, and Vascular Biology. 2005;25:436

JAMA. 2008;299(11):1345-1350

3 years, 11 months ago

CytoEpigenetics XVIII. Membrane lipid architectonics organized for cell cycle and both nuclear and mitochondrial biochemical mediation of gene expression. Dr. Dan Guerra. 05 June 2022

References

Dr Guerra's synthesis of lecture material

Histochemistry and Cell Biology volume 145, pages275–286 (2016)

Biol Rev Camb PhilosSoc.. 2018 M…

3 years, 11 months ago

CytoEpigenetics XVII. The role of ceramide metabolism in epigenetic and bioenergetic cross talk among multiple subcellular compartments. Dr Dan Guerra. 03June2022 Authentic Biochemistry Podcast

References

Dr Guerra's synthesis of lectures

Scientific Reports volume 5, Article number: 15292 (2015)

3 years, 11 months ago

CytoEpigenetics XVI. The Mt DNA replicase and helicase enzymes are epigenetically nuclear encoded and localize to the mitochondrial membrane into lipid rafts containing cholesterol. DJGPhD. 2June2022

References

Dr Guerra's lecture sytheses

Scientific Reports volume 5, Article number: 15292 (2015)

3 years, 11 months ago

CytoEpigenetics XV.An AMPK phosphorylation cascade promoting mTOR pro-translational induction of NFkappa-B SASP transcription is modulated by NAD+ Sirtuin and PARP during Chromatin retailoring.DJGPhD

References

Dr Guerra's synthesis of the relevant literature

BioEssays, Volume: 39, Issue: 5, First published: 20 February 2017.

Front Cardiovasc Med.…

3 years, 11 months ago

CytoEpigenetics XIV. The details of AMPK mediated control over DNA methyl transferase thus coordinating bioenergetics with cell fate via the epitranscriptome. DJGPhD. 25.5.22

References

Dr. Guerra's synthesis of the epitranscriptome lecture notes

Sci Signal. 2017 Jan 31; 10(464): eaaf7478.

3 years, 11 months ago

CytoEpigeneticsXIII. Epitranscriptomics of Fatty acid Utilization is a driver of Heart-Failure associated Cardiorenal disease. Dr daniel J. Guerra. Authentic Biochemistry.22.5.22

References

Sci Signal. 2017 Jan 31; 10(464): eaaf7478

Prostaglandins Leukot Essent Fatty Acids. 2015 Jul;98:49-55

Nat Commun. 2020; 11: 4664.

Int J B…

4 years ago

CytoEpigenetics XII. The central role of mitochondria in regulating cell fate and metabolic switching is necessary and universal in epigenetic modification of gene expression. DJGPhD.20.5.22

References

Dr Guerra's lecture notations and synthesis

Cell. 2014 Dec 18; 159(7): 1615–1625

Nat Commun. 2020; 11: 102.

4 years ago

CytoEpigenetics XI. The interactive intermediary metabolic architectonic of methylation and acetylation in epigenetic mediation of gene expression between the mitochondria and nucleus. DJGPhD.17.5.22

References

Dr Guerra's lecture notes

Nat Commun. 2020; 11: 102.

Cold Spring Harb Perspect Biol. 2013 Sep; 5(9): a017947.

4 years ago

CytoEpigenetics X. The IDH isofrom roles of mutant, hypoxic and constitutive activities mediate DNA, RNA and Histone3 Lys methylation patterns thus redirecting gene expression.DJGPhD.15.5.22

References

Dr Guerra's letures/reasoning

SCIENCE ADVANCES • 22 May 2019 • Vol 5, Issue 5

Cell MetabolismVolume 22, Issue 2, 4 August 2015, Pages 304-…

4 years ago