Podcast Episodes

ImmunoEpigenetics XXXXIII. In silico analysis of Rheumatoid Arthritis methylation patterns fails to obtain a general rule for epigenetic regulation of gene expression.DJGPhD07March23. ABPe

References

Int J Hematol 2022. 116, 828–836

Cancer Immunol Res (2022) 10 (1): 87–107

Front Immunol. 2022; 13: 881191

Nature Reviews Immunology 2018. …

3 years, 7 months ago

ImmunoEpigenetics XXXXII. T-ALL Homeobox A gene alteration of MEF2C expressional variation linked to T-cell differentiation blockade as regulated by CaMK and HDAC4/HDAC5. DJGPhD. 05March23.

References

Biochem J 2012 444(1):105-114

Epigenetics. 2015 May; 10(5): 418–430.

Nature Reviews Immunology volume 2018. 18, pages 617–634 

3 years, 7 months ago

ImmunoEpigenetics XXXXI. From Programmed Cell Death to Homeobox gene clusters, T-ALL leukaemias involve epigenetic events. DJGPhD.05March23. Authentic Biochemistry Podcast

References

Genes & Diseases Available online 26 December 2022

Int J Mol Sci. 2021 May; 22(10): 5317

Haematologia 2016. Vol. 101 No. 6  June.

Blood (2…

3 years, 7 months ago

ImmunoEpigenetics XXXX. Transcription factor complex permutaions combine with histone acetylomic and methylomic covalent mofications in T -ALL disease. DJGPhD. 04 March 2023. Authentic Biochemistry.

References

Nature Reviews Immunology volume 18, pages 617–634 (2018)

Genes (Basel). 2021 Aug; 12(8): 1118.

3 years, 7 months ago

ImmunoEpigenetics XXXIX. T cell acute lymphoblastic leukaemia genetics and epigenetics: the role of chromatin retailoring via histone LYS acetylation/deacetylation event ontology. DJGPhD.3March23

References

Genes (Basel). 2021 Aug; 12(8): 1118.

Nature Reviews Immunology 2018. volume 18, pages 617–634.

3 years, 7 months ago

ImmunoEpigenetics XXXVIII. Tcell receptor activation and the PIP3/AKT/mTORCI/mTORCII control over cytokine expression:a primer. DJGPhD.2March2023.Authentic Biochemistry Podcast.

References

Guerra's immunology lectures

Experimental & Molecular Medicine volume 51, Article number: 80 (2019)

Genes (Basel). 2021 Aug; 12(8): 1118

3 years, 7 months ago

ImmunoEpigenetics XXXVII. Differential substrates for the Adenylate Cyclase-PKA phosphorylation cascade distributes assymetric inflammatory, hormonal and metabolic sequalae. DJGPhD.01March23.

REferences

Dr Guerra's graduate biochemistry lectures

J Biol Chem. 2013 Mar 8; 288(10): 7137–7146

3 years, 7 months ago

ImmunoEpigeneticsXXXVI. Tumor-specific methylation respondent transcription of Adenylate Cyclase 2 may be linked to differential cytokine expression controlling T cell activation. DJGPhD.01March23.

References

Naunyn Schmiedebergs Arch Pharmacol . 2014 Apr;387(4):329-39.

J Biol Chem. 2013 Mar 8; 288(10): 7137–7146

J Anim Sci. 1998 Jan;76(1):160-7…

3 years, 7 months ago

Immunoepigenetics XXXIV. Methylation signatures in neoplasias1. DJGPhD. Authentic Biochemistry Podcast Productions. 26.2.23

References

Journal of Bone Oncology 2017. Volume 9, November.  Pages 34-40

Journal of Disease and Global Health 15(3): 22-47, 2022.ISSN: 2454-1842, N…

3 years, 7 months ago

ImmunoEpigenetics XXXIII. Crisper CAS , small molecule,and LOXP-CRE targeting of SDH/ComplexII decrease Th1 cytokine production: Standard Oxidation Potentials and TCA anapleurotic involvement.DJGPhD.

References

Nature. 2019 Jul; 571(7765): 403–407

Dr Guerra's lectures

3 years, 8 months ago