Podcast Episodes

ImmunoEpigenetics X(A). Inhibtion of histone trimethyl-Lys demethylases as arbiter of controlling human Acute Myeloid Leukaemia (AML). Dr Daniel J. Guerra. 30.12.22. Authentic Biochemistry

References

The Journal of Biological Chemistry16/2/2018293: 2422-2437.

Anal Cell Pathol (Amst). 2018; 2018: 787.1814

Nature Reviews Drug Discovery. S…

3 years, 6 months ago

ImmunoEpigeneticsX. Inhibtion of histone trimethyl-Lys demethylases as arbiter of controlling human Acute Myeloid Leukaemia (AML). Dr Daniel J. Guerra. 30.12.22. Authentic Biochemistry

References

J Cancer Res Clin Oncol. 2018; 144(6): 1065–1077

Nature Reviews Drug Discovery. Sep2014, Vol. 13 Issue 9, p673-691

Anal Cell Pathol (Amst)…

3 years, 6 months ago

Diabetes XXV. Obesity linked disruption of adipose mediated endocrine hormone control over fatty acid turnover from TAG leads to T2D in humans. Dr. Daniel J. Guerra. 3April22.Authentic Biochemistry

References

Dr. Guerra lecture materials

Progress in Lipid Research Volume 74, April 2019, Pages 145-159

3 years, 6 months ago

Holiday Ethanol Abuse Lecture I. EtoH ingestion, while intoxicating redox metabolism is also a membrane lipid -protein interacting agent that corrupts inwardly rectifying K voltage gated channels.

References

Dr Guerra EtOH lectures

PNAS November 5, 2013 vol. 110 no. 45

Alcohol, 2017-12-01, Volume 65, Pages 51-62

3 years, 6 months ago

ImmunoEpigeneticsIX. Promoter/Enhancer proximal and distal epigenetic signatures and transcription factor protein heterogeneity compose gene expression event ontology.DJGPhD.29.12.22.AuthenticBiochem

References

Proc Natl Acad Sci U S A. 2021 Nov 16; 118(46)

Nat Rev Mol Cell Biol. 2021 Dec 1; 22(12): 815–833. 

3 years, 6 months ago

More "mere" epistemology opening a door to metaphysics II. Non-canonical epi-rational and epi-empirical retailoring of understanding and imagination via research scientific endojectification.DJGPhD.

References

Dr. Guerra's ongoing flight into the telos of research science.

3 years, 6 months ago

ImmunoepigeneticsVIII. Protective immunotolerant neonate Th1 inactivity involves IL-12 p35subunit promoter methylation. DJGPhD.23.12.22. Authentic Biochemistry Podcast

References

Trends in Immunology. REVIEW. 2017. VOLUME 38, ISSUE 4, P287-297.

J Biomed Sci. 2014 Aug 19;21(1):76.

3 years, 6 months ago

Holiday Ethanol Use VIII. EtOH induced cAMP /CREB associated PKA kinase driven phosphorylation cascade co-opts the TLR4-mediated neuroinflammatory/neurotoxic CNS-microglial axis.DJGPhD.22.12.22.AB.

References

Neural Plasticity. 2019; 2019: 1648736.

Molecular Pharmacology May 2017, 91 (5) 451-463.

3 years, 6 months ago

Holiday Ethanol Use VII. EtOH exposure precipitates chromatin methylation associated MCH and chemokine involvement linking arousal, reward and inflammation. DJGPhD.21.12.22 Authentic Biochem.

References

PLoS One. 2011;6(5):e17711

J Neuroinflammation. 2020; 17: 207

Front Neurosci. 2019 Nov 26;13:1280

3 years, 6 months ago

Mere Epistemology Knocking on Metaphysics for a late December Evening. I. DJGPhD.21 December 2022 Authentic Biochemistry Podcast

References

Dr Guerra's ideas and concepts concerning the epistemics of research science . Lecture I.

3 years, 6 months ago