Podcast Episodes

ImmunoEpigenetics82.Innate lymphoid progenitor antibody-directed single cell DNAse hypersenitive site analysis of transcription factor specific histone methylation and acetylation modifications.DJGPhD

References

Nat Protoc. 2017 Nov;12(11):2342-2354

Annual Review of Immunology 2021. Volume 39. pp 279-311

Immunity 2022. Volume 55, Issue 8. Pages 14…

3 years, 4 months ago

ImmunoEpigenetics 81.Innate lymphoid cells lack antigen receptors and are differentiated into multiple linneages via epigenetic priming of nucleosomal regions proximal to cell-specific TF's.DJGPhD.

References

Immunity 2022. 55, Issue 8. Pages 1402-1413.

Methods Mol Biol. 2018;1675:167-181.

Experimental & Molecular Medicine 2019. volume 51, Arti…

3 years, 4 months ago

ImmunoEpigenetics80.T lymphocyte biochemical communications are triggered epigentically and via membrane lipid molecular species recombination: A dialectical event ontological view. DJGPhD.17.6.23

Reference

Authentic Biochemistry Lecture synthesis

3 years, 4 months ago

ImmunoEpigenetics79. T lymphocyte DPPA induced HSP27 deoligomerization-activating DGK-a associated anergy is linked to cancer cell proliferation phenotypes. DJGPhD.16.6.23b Authentic Biochemistry

Reference

J BiolChem. 2023 Mar; 299(3): 103019.

3 years, 4 months ago

ImmunoEpigenetics 78. Classical ergodic forward deterministics do not explain biological systems; biochemical phenomena are tuned for uncertain events. DJGPhD.16.6.23. Authentic Biochemistry Podcast

References

J Biol Chem 2017 292: 20481.

Critique if Pure Reason.1781. Kant,I.

Guerra,2023. manuscripts in preparation

3 years, 4 months ago

ImmunoEpigenetics77. T cell membrane phospholipase D mediated PA deprotonation as a biosensor for an electrostatic/hydrogen-bond signal transductionDJGPhD.15.6.23. Authentic Biochemistry Podcast.

References

The Journal of Biological Chemistry 2007.282,11356-11364.

BMC Biology 2011. 9:85

Cancer Res . 2011 Jan 15;71(2):293-7.

J BiolChem. 2023 Ma…

3 years, 4 months ago

Interum lecture VI. Entropic forces and the ergodic hierarchy of GPCR-linked phsopholipase phase space postioning temporality. DJGPhD.13.6.23

References

ACS Omega. 2019 Nov 26; 4(22):19526–19547

Guerra: general thermodynamics lectures

3 years, 4 months ago

Interum Lecture V. Semi-closure on free energy and enthalpic involvement in leptin/AMPK mediated orexigenic states . DJGPhD.12June23.Authentic Biochemistry Podcast

Reference

Guerra lecture material

3 years, 4 months ago

Interum Lecture IV. MBD:DNAMolecular Dynamics video lecture!

https://youtu.be/O2CpwFLy0zI

3 years, 4 months ago

Interum Lecture III. Protein methylation binding domain association with substrate CpG alters equilibrium torsion angle (epsilon-zeta) conformational states via enthalpic-free energy conservation.

References

Mol Informatics. 2012 Feb;31(2):114-22.

Nat Struct Mol Biol. 2017 Jun; 24(6):544–552

Guerra: chemical thermodynamics lectures

3 years, 4 months ago