Podcast Episodes

ImmunoEpigenetics59. The P53/AKT/PHLDA3 axis over tumorigenicity is controlled by endomembraneous targeting via glycerol lipid PhosphatidylInositol bis-phosphate (PIP2) phosphorylation to PIP3.5.12.23

References

Int J Mol Sci. 2020 Jun; 21(11): 4098.

Authentic Biochemistry lectures :ImmunoEpigenetics 56-58

3 years, 2 months ago

ImmunoEpigenetics 58. Epigenetic mechanisms role in Loss of Heterozygosity (LOH) in TSG's advancing targeting of solid tumors via pharmacotherapeutic CAR-T cells. DJGPhD 27.4.23. Authentic Biochem.

References

BMC Medical Genomics. 2015. volume 8, Article number 45.

Journal for ImmunoTherapy of Cancer 2022;10:e003826.

3 years, 2 months ago

ImmunoEpigenetics 57. Plasmacytoid dendritic cell neoplasias and the CAR-T cell tumor microenvironment exposure altering epigenetic TF regulation leading to diverse differentiation. DJGPhD.20.4.23

References

Current Oncology Reports. 2020. 1534-6269, May 15, Vol. 22, Issue 6.

Cell. 2021 Dec 9; 184(25):6081–6100.e26.

3 years, 2 months ago

ImmunoEpigenetics 56. Dendritic cell immunobiochemistry introductions. DJGPhD. Authentic Biochemistry 15.4.23

References

Autoimmunity. 2012 Aug;45(5):333-47

Clinical and Experimental Rheumatology 2019: One year in review 2019: systemic lupus erythematosus

Tr…

3 years, 3 months ago

ImmunoEpigenetics55. ILC and Treg differentiation is mediated by acetylation and methylation epigenegtic authorship at discrete TF binding site domains.DJGPhD.14.4.23. Authentic Biochemistry

References

Cell Reports 2015 10, 2043-2054DOI

ID2_HUMAN,Q02363

Experimental & Molecular Medicine 2019. volume 51, Article number: 80.

3 years, 3 months ago

Immunoepigenetics 54. Macrophages, T lymphocytes and neutrophils each comply with epigenetic alterations to mediate the inflammatory response. DJGPhD.12April.2023.Authentic Biochemistry

References

Guerra's notes

3 years, 3 months ago

ImmunoEpigenetics 53.The metaphysics of biochemical control within epigenetic alteration of gene expression as obtained in macrophage mediated immune activation. DJGPhD.7April23'Authentic Biochem

References

Dr Guerra's lecture notes-Immunology

DJGPhD writings on Middle Platonist Metaphysics in Biochemistry: unpublished

Curr Opin Biotechnol. 2…

3 years, 3 months ago

ImmunoEpigenetics 52. Integration of intermediary metabolism with epigenetic modification of immune cell activation and proliferation.DJGPhD. 5April23. Authentic Biochemistry Podcast.

References

Curr Opin Biotechnol. 2020 Jun; 63: 111–117

Epigenomics. 2019. VOL. 11, NO. 68 May

Front.Genet., 23 October 2018 Sec. Epigenomics and Epig…

3 years, 3 months ago

ImmunoEpigenetics 51. The Glutamine contribution to tumor bioenergetics and lipogenesis and the role of storage TAG in macrophage pro-inflammation. DJGPhD. 29.3.23

References

Nature Communications 2020.volume 11, Article number: 4107.

Nutrire 2016. volume 41, Article number: 14

3 years, 3 months ago

ImmunoEpigenetics 50. Malic Enzyme serves as a cytosolic circuit to generate pyruvate from glutamine to drive cancer cell division by altering TCA flux and indirectly, cell cycle progression.DJGPhD

References

Cell 2012 148DOI: (10.1016/j.cell.2012.01.031)

Biotechnology Journal 2016. Volume11, Issue1 Special Issue: Biotech Methods and Advances: …

3 years, 3 months ago