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ImmunoEpigenetics 73. The dialectical synthesis of adipose PPAR-gamma mediated fatty acid binding protein4 expression in foam cell formation and subsequent adipokine contribution to insulin secretion
References
Cells. 2019 Mar; 8(3): 227
Chest. 2016 Jul; 150(1): 91–101
JCI Insight. 2016 Nov 17; 1(19): e87748.
3 years, 1 month ago
ImmunoEpigenetics72. Chemistry of reactive oxygen/nitrogen radical species as adipose pathobiochemical sequalae to obesity via M1 macrophage polarity involving adipose and vasculature pathophysiology.
References
Inn Med (Heidelb). 2023 Apr;64(4):313-322
JBC 2001.Volume 276, Issue 31, Pages 28799-28805
Frein, Daniel. 2006. “Signaling and Redox Regul…
3 years, 1 month ago
ImmunoEpigenetics 71. Insulin receptor corruption is mediated by high circulating fatty acids, in situ DAG-PKCepsilon induced phosphorylation and membrane protein aggregation in obese diabetics.DJGPhD
References
Guerra Biochemistry lecture archives
Nat Metab. 2022 Sep;4(9):1202-1213
Mol Cell. 2008 May 23; 30(4): 403–414
J Clin Invest. 2016 Nov 1; 1…
3 years, 1 month ago
ImmunoEpigenetics 70.Obesity-linked adipose resident macrophage (M1)polarization meta-inflammation leads to Insulin Resistance via fatty acid oxygenation in situ. DJGPhD.01June2023.Authentic Biochem.
References
Graduate Biochemistry lectures-Guerra
Front Immunol. 2021; 12: 746151
3 years, 1 month ago
Intermediary Metabolism Lecture. Covalent modification of enzymes and transcription factors alter bioenergetics and the pro-inflammatory response in obese vs. healthy patients.31.5.23 DJGPhD
References
Guerra general graduate biochemistry lecture
Immunol Res. 2020 Feb;68(1):28-38. doi: 10.1007/s12026-020-09125-9.
3 years, 1 month ago
See the youtube video in the show notes
https://youtu.be/es0RrQHHXl0
3 years, 1 month ago
ImmunoEpigenetics 69. Lipoprotein and cargo cholesterol in the epigenetic regulation of the tumor microenvironment secreted pleckstrin convertase corrupting CD8+ Tcell cholesterol uptake and potency.
References
Journal of Experimental & Clinical Cancer Research 2022.volume 41, Article number: 303.
Protein Cell. 2021 Apr; 12(4): 240–260.
J Cell Bi…
3 years, 1 month ago
Graduate Biochemistry Lecture III. Dietary lipid control over neuroendocrine system involves multiple organ systems in contact with immune surveilance. DJGPhD. 24.5.23B Authentic Biochemistry
References
Dr. Guerra's lecture archives.
3 years, 1 month ago
Graduate Biochemistry Lecture.II. Lipid digestion and enterocyte localized neuroendocrine secretion proximal to chylomicron assembly.Dr Daniel J. Guerra. Authentic Biochemistry Podcast 19.5.23.
References
Dr. Guerra's lipid lectures
J Diabetes Investig. 2019 Nov; 10(6): 1430–1437.
3 years, 1 month ago
Special Graduate Biochemistry Lecture! Lipoproteins I. Dr Daniel J. Guerra. Authentic Biochemistry Podcast 19.5.23.
Reference
Dr Guerra: Graduate Biochemistry lecture material.
3 years, 1 month ago