Podcast Episodes

ImmunoEpigenetics87. Competitive inhibition of HMGCoA-R may enhance apoptosis while blocking cholesterologenesis and GGPP covalent modification of signaling kinases to thwart ETP-All in cell culture.

References

JBC.2002. Volume 277, ISSUE 2, P1128-1138.

Cancer Discov. 2022 Mar 1; 12(3): 856–871.

Guerra lectures-lipid metabolic regulation

Guerra …

3 years ago

ImmunoEpigenetics86. Could regimented titrating statin pharmacotherapy be useful in controlling early T lymphoid progenitor cell ETP-ALL via an epigenetic mechansim? DJGPhD.27.6.23. Authentic Biochem

Reference

Cancer Discov. 2022 Mar 1; 12(3): 856–871.

3 years ago

ImmunoEpigenetics85.Epigenetic plasticity-induced chromatin retailoring involving the mevalonic acid -prenyl lipid pathway promotes Early T-cell Precursor Acute Lymphoblastic Leukemia. DJGPhD.24.6.23

References

Cancer Discov. 2022 Mar 1; 12(3): 856–871.

Sci Signal. 2015 Mar 31;8(370):re4

3 years ago

ImmunoEpigenetics84. T cell and ILC transcription factor and cytokine signaling coordination to accelerate a combined innate/acquired immune response requires discrete epigenetic programming. DJGPhD.

References

J Exp Med. 2017 Jul 3;214(7):1861-1876

Immunol Rev. 2014 Sep;261(1):62-83

Int J Mol Sci. 2022 Mar; 23(5): 2878.

Immunity 2022. Volume 55,…

3 years ago

ImmunoEpigenetics 83. Epistemic and metaphysical considerations of immune cell epigenetic reprogramming obtaining biochemical event ontologies. DJGPhD.23.6.23. Authentic Biochemistry Podcast

References

Guerra: logical propositions and dialectical syntheses

Annual Review of Immunology2021. Volume 39: 279-311

3 years ago

ImmunoEpigenetics82.Innate lymphoid progenitor antibody-directed single cell DNAse hypersenitive site analysis of transcription factor specific histone methylation and acetylation modifications.DJGPhD

References

Nat Protoc. 2017 Nov;12(11):2342-2354

Annual Review of Immunology 2021. Volume 39. pp 279-311

Immunity 2022. Volume 55, Issue 8. Pages 14…

3 years ago

ImmunoEpigenetics 81.Innate lymphoid cells lack antigen receptors and are differentiated into multiple linneages via epigenetic priming of nucleosomal regions proximal to cell-specific TF's.DJGPhD.

References

Immunity 2022. 55, Issue 8. Pages 1402-1413.

Methods Mol Biol. 2018;1675:167-181.

Experimental & Molecular Medicine 2019. volume 51, Arti…

3 years ago

ImmunoEpigenetics80.T lymphocyte biochemical communications are triggered epigentically and via membrane lipid molecular species recombination: A dialectical event ontological view. DJGPhD.17.6.23

Reference

Authentic Biochemistry Lecture synthesis

3 years, 1 month ago

ImmunoEpigenetics79. T lymphocyte DPPA induced HSP27 deoligomerization-activating DGK-a associated anergy is linked to cancer cell proliferation phenotypes. DJGPhD.16.6.23b Authentic Biochemistry

Reference

J BiolChem. 2023 Mar; 299(3): 103019.

3 years, 1 month ago

ImmunoEpigenetics 78. Classical ergodic forward deterministics do not explain biological systems; biochemical phenomena are tuned for uncertain events. DJGPhD.16.6.23. Authentic Biochemistry Podcast

References

J Biol Chem 2017 292: 20481.

Critique if Pure Reason.1781. Kant,I.

Guerra,2023. manuscripts in preparation

3 years, 1 month ago