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ImmunoEpigenetics 57. Plasmacytoid dendritic cell neoplasias and the CAR-T cell tumor microenvironment exposure altering epigenetic TF regulation leading to diverse differentiation. DJGPhD.20.4.23
References
Current Oncology Reports. 2020. 1534-6269, May 15, Vol. 22, Issue 6.
Cell. 2021 Dec 9; 184(25):6081–6100.e26.
3 years, 1 month ago
ImmunoEpigenetics 56. Dendritic cell immunobiochemistry introductions. DJGPhD. Authentic Biochemistry 15.4.23
References
Autoimmunity. 2012 Aug;45(5):333-47
Clinical and Experimental Rheumatology 2019: One year in review 2019: systemic lupus erythematosus
Tr…
3 years, 1 month ago
ImmunoEpigenetics55. ILC and Treg differentiation is mediated by acetylation and methylation epigenegtic authorship at discrete TF binding site domains.DJGPhD.14.4.23. Authentic Biochemistry
References
Cell Reports 2015 10, 2043-2054DOI
ID2_HUMAN,Q02363
Experimental & Molecular Medicine 2019. volume 51, Article number: 80.
3 years, 1 month ago
Immunoepigenetics 54. Macrophages, T lymphocytes and neutrophils each comply with epigenetic alterations to mediate the inflammatory response. DJGPhD.12April.2023.Authentic Biochemistry
References
Guerra's notes
3 years, 1 month ago
ImmunoEpigenetics 53.The metaphysics of biochemical control within epigenetic alteration of gene expression as obtained in macrophage mediated immune activation. DJGPhD.7April23'Authentic Biochem
References
Dr Guerra's lecture notes-Immunology
DJGPhD writings on Middle Platonist Metaphysics in Biochemistry: unpublished
Curr Opin Biotechnol. 2…
3 years, 1 month ago
ImmunoEpigenetics 52. Integration of intermediary metabolism with epigenetic modification of immune cell activation and proliferation.DJGPhD. 5April23. Authentic Biochemistry Podcast.
References
Curr Opin Biotechnol. 2020 Jun; 63: 111–117
Epigenomics. 2019. VOL. 11, NO. 68 May
Front.Genet., 23 October 2018 Sec. Epigenomics and Epig…
3 years, 1 month ago
ImmunoEpigenetics 51. The Glutamine contribution to tumor bioenergetics and lipogenesis and the role of storage TAG in macrophage pro-inflammation. DJGPhD. 29.3.23
References
Nature Communications 2020.volume 11, Article number: 4107.
Nutrire 2016. volume 41, Article number: 14
3 years, 1 month ago
ImmunoEpigenetics 50. Malic Enzyme serves as a cytosolic circuit to generate pyruvate from glutamine to drive cancer cell division by altering TCA flux and indirectly, cell cycle progression.DJGPhD
References
Cell 2012 148DOI: (10.1016/j.cell.2012.01.031)
Biotechnology Journal 2016. Volume11, Issue1 Special Issue: Biotech Methods and Advances: …
3 years, 2 months ago
ImmunoEpigenetics49.SiRNA knockdown of ME1 increases Haeme Oxygenase activity in both glucose supplemented and deprived cancer cells. The Pseudoparadox of epigenetic control over metabolism. DJGPhD
References
Dr Guerra's lectures and spontaneous expectorations.
Molecular Cancer 2020. volume 19, Article number: 39
3 years, 2 months ago
ImmunoEpigenetics48. Importance of malic enzyme isoform subcellular distribution using 13CNMR -U13C C6 glucose isotopomer detection of pathway intermediates:GSIS vs. cancer.DJGPhD.21.3.23
References
Methods Enzymol. 2009; 457: 425–450
Endocrinology, Volume 155, Issue 5, 1 May 2014, Pages 1653–1666
Am J Physiol Endocrinol Metab. 2008 De…
3 years, 2 months ago