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ImmunoEpigenetics 70.Obesity-linked adipose resident macrophage (M1)polarization meta-inflammation leads to Insulin Resistance via fatty acid oxygenation in situ. DJGPhD.01June2023.Authentic Biochem.
References
Graduate Biochemistry lectures-Guerra
Front Immunol. 2021; 12: 746151
2 years, 11 months ago
Intermediary Metabolism Lecture. Covalent modification of enzymes and transcription factors alter bioenergetics and the pro-inflammatory response in obese vs. healthy patients.31.5.23 DJGPhD
References
Guerra general graduate biochemistry lecture
Immunol Res. 2020 Feb;68(1):28-38. doi: 10.1007/s12026-020-09125-9.
2 years, 11 months ago
See the youtube video in the show notes
https://youtu.be/es0RrQHHXl0
2 years, 11 months ago
ImmunoEpigenetics 69. Lipoprotein and cargo cholesterol in the epigenetic regulation of the tumor microenvironment secreted pleckstrin convertase corrupting CD8+ Tcell cholesterol uptake and potency.
References
Journal of Experimental & Clinical Cancer Research 2022.volume 41, Article number: 303.
Protein Cell. 2021 Apr; 12(4): 240–260.
J Cell Bi…
2 years, 11 months ago
Graduate Biochemistry Lecture III. Dietary lipid control over neuroendocrine system involves multiple organ systems in contact with immune surveilance. DJGPhD. 24.5.23B Authentic Biochemistry
References
Dr. Guerra's lecture archives.
3 years ago
Graduate Biochemistry Lecture.II. Lipid digestion and enterocyte localized neuroendocrine secretion proximal to chylomicron assembly.Dr Daniel J. Guerra. Authentic Biochemistry Podcast 19.5.23.
References
Dr. Guerra's lipid lectures
J Diabetes Investig. 2019 Nov; 10(6): 1430–1437.
3 years ago
Special Graduate Biochemistry Lecture! Lipoproteins I. Dr Daniel J. Guerra. Authentic Biochemistry Podcast 19.5.23.
Reference
Dr Guerra: Graduate Biochemistry lecture material.
3 years ago
ImmunoEpigenetics 68. Closure on atherosclerosis and CVD linking transcription factors and membrane receptors to oxidation of PUFA's and oxysterol resulting in methylation of ABCG and SREB promoters
References
Arterioscler Thromb Vasc Biol . 2021 Jan;41(1):153-166.
Clinical Epigenetics 2021. volume 13, Article number: 7.
https://www.sciencedire…
3 years ago
ImmunoEpigenetics 67. Pathobiochemical alteration of cholesterol oxides mediated via cytochrome P450 and dehydro -reductases link atherosclerosis and the CTX/SLO motor neuron diseases. DJGPhD
References
JLR 2014 55(6) Pages 1165-1172.
JLR 2018 59(6): 1058–1070.
3 years ago
ImmunoEpigenetics 66. The NOX/PHOX/DUOX enzymes in atherosclerosis, thyroid hormonogenesis and thyroid tumorigenesis. An epigenetic telos from oxidized lipid to altered transcription patterns.DJGPhD.
References
PLoS ONE 2012. 7(4): e3440
Steroids 2021. Volume 172, August, 108854
Antioxidants 2019, 8(5), 126
3 years ago