Podcast Episodes

ImmunoEpigenetics97.Bcell maturation involves a multilevel epigenetic mark-up of differentiating pathways to subsequently respond to T cell activation upon 2nd signal stimulation. DJGPhD.24.7.23

References

Cellular & Molecular Immunology. 2022. volume 19, pages 1215–1234.

Front. Cell Dev. Biol. 2022. 07 January Sec. Epigenomics and Epigenetic…

2 years, 11 months ago

ImmunoEpigenetics96. APC-agMHCII and Bcell:Tcell synapse interactions yield subsequent plasma cell antibody production under the H3K4me3 epigenetic alteration of chromatin accessibility.DJGPhD.23.7.23

References

J Immunol. 2014 Aug 15; 193(4): 1531–1537

Immunology lecture notes-Guerra

2 years, 11 months ago

Mountain Pass Adventure I. The "five best" and an excursion into asymmetry. Dr. Daniel J. Guerra. 22.7.23. Authentic Biochemistry Podcast.

Inspirations

A hot summer day and what passes as a ponder on the asymmetric.

2 years, 11 months ago

ImmunoEpigenetics 95. Does H3K4 trimethylation play a quantitative or qualitative role in nascent activation of neonatal naive T cells toward a specific polarity of gene expression?DJGPhD.20.7.23

Reference

Immunol Cell Biol. 2022 Aug; 100(7):562–579.

2 years, 11 months ago

ImmunoEpigenetics. 94. Neonate TCR stimulation and subsequent signaling circumventing TCR specificity differ from adult activation and cytokine expression. DJGPhD. 19.7.23. Authentic Biochemistry

Reference

Immunol Cell Biol. 2022 Aug; 100(7):562–579.

2 years, 11 months ago

ImmunoEpigenetics 93. tTREG's not only control Th differentiation and proliferation but in an HLA-antigen mediated specificity thus differentiating CD4+ vs CD8+ inflammation as directed by 6mA.

References

Signal Transduction and Targeted Therapy 2021.volume 6, Article number: 412.

Nature Immunology. 2022. volume 23, pages 1208–1221.

3 years ago

ImmunoEpigenetics 92. thymic Treg populations alter Th1 differentiation. Antigen presenting DC's coordinate TCR with associated membrane proteins to support activation via PM lipid sequence.DJGPhD.

References

J Biol Chem. 2021 Jul;297(1):100900

Immunol Rev. 2014 May; 259(1):88–102.

3 years ago

ImmunoEpigenetics91. WTAP conditional deletion via LoxPCre controlled by FoxP3 obtains a Treg phenotype incapable of supressing murine spontaneous colitis. DJGPhD. 15.7.23. Authentic Biochemistry.

Reference

Nature Immunology 2022. volume 23, pages 1208–1221.

3 years ago

ImmunoEpigenetics90. Tcell receptor organization activation and adaptor protein ligand molecular signaling is regulated down stream by 6methyl mRNA speciation.DJGPhD.7July2023.Authentic Biochemistry

References

Nature Immunology 2022. volume 23, pages 1208–1221

Signal Transduction and Targeted Therapy 2021. volume 6, Article number: 412.

3 years ago

Enzyme Kinetics sensu strictu. The Michaelis Menten equations and precison of the kcat. DJGPhD.9July23b. Authentic Biochemistry Podcast.

References

Guerra lectures archives

3 years ago