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BioMedical Portraits I. Part 4 Loss of female gonadal E2 production plus CNS E2 Receptor expression post-menopause involves irreversible alterations in metabolism:implications for neuroprotection.
References
Essays Biochem. 2021 Nov; 65(6): 913–925
Front. Endocrinol. 2022. AUGUST. v.13 .Sec. Molecular and Structural Endocrinology …
2 years, 11 months ago
BioMedical Portraits I. part 3 Estrogen receptor heterogeneity in signaling and transcription and the distinctions between model-murine and human reproductive and CNS biochemistry.DJGPhD 05AUG23
Reference
Essays Biochem. 2021 Nov; 65(6): 913–925
2 years, 11 months ago
BioMedical Portraits I. Part 2.Murine model Alzheimer's Disease is poorly linked to menopuase or Vascular contributions to Cognitive Impairment & Dementia (VCID).DJGPhD 05AUG23
References
Essays Biochem. 2021 Nov; 65(6): 913–925
Biol Sex Differ. 2023; 14: 34.
2 years, 11 months ago
BioMedical Portraits I. Alzheimers Disease in Ageing Females is linked to CNS-sphingomyelinase mediated ketogenesis and VCID.Lecture 1. DJGPhD.3AUG23.Authentic Biochemistry
References
Biol Sex Differ. 2023; 14: 34
J Cell Sci 2005;118:4605-4612
EBioMedicine. 2015 Dec; 2(12): 1888–1904
PLoS Genet. 2013 Jun; 9(6): e1003556
2 years, 11 months ago
From Intellections' pathway into the forest of metaphysics.II DJGPhD.30.July 2023b. Authentic Biochemistry Podcast
Reference
Some light on the forest floor of wisdom
2 years, 11 months ago
The Road to Intellection I. DJGPhD. 30.7.23. Authentic Biochemistry Podcast
References
Experience et al.
2 years, 11 months ago
ImmunoEpigenetics 100B. Fine. The apodictic recombination-dependent TCR and Ig receptor system is mediated by epigentic modifications.DJGPhD.29.7.23. Authentic Biochemistry
References
Mol Cancer. 2023 Apr 10;22(1):69
Proc Natl Acad Sci U S A. 2019 Jun 18;116(25):12410-12415
Semin Immunol. 2010 Dec; 22(6): 311–312
2 years, 11 months ago
ImmunoEpigenetics100A. The Tcell repose and ILC differentiation via E vs ID chromatin remodeling antagonism. DJGPhD.28.7.23. Authentic Biochemistry Podcast.
Reference
Front Immunol.2022; 13: 890056.
previous IE lectures 1-3.
2 years, 11 months ago
ImmunoEpigenetics 99. Tregs can foster a massive tumor microenvironment inhibition of T-eff cell populations via neo-antigen activation from dying tumor cells leading to cancer progression. DJGPhD
Reference
Cancers (Basel). 2021. Apr; 13(8): 1850.
2 years, 11 months ago
ImmunoEpigenetics 98. TCR mediated protection from neonate infection is naturally suppressed. BCG VAX may be a treatment against Type 1 Diabetes by increasing Treg mediated autoimmune suppression.
References
NPJ Vaccines. 2018; 3: 23.
Immunol Cell Biol. 2022 Aug; 100(7): 562–579
2 years, 11 months ago