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ImmunoEpigenetics84. T cell and ILC transcription factor and cytokine signaling coordination to accelerate a combined innate/acquired immune response requires discrete epigenetic programming. DJGPhD.
ImmunoEpigenetics84. T cell and ILC transcription factor and cytokine signaling coordination to accelerate a combined innate/acquired immune response requires discrete epigenetic programming. DJGPhD.

References

J Exp Med. 2017 Jul 3;214(7):1861-1876

Immunol Rev. 2014 Sep;261(1):62-83

Int J Mol Sci. 2022 Mar; 23(5): 2878.

Immunity 2022. Volume 55,…

2 years, 11 months ago

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ImmunoEpigenetics 83. Epistemic and metaphysical considerations of immune cell epigenetic reprogramming obtaining biochemical event ontologies. DJGPhD.23.6.23. Authentic Biochemistry Podcast
ImmunoEpigenetics 83. Epistemic and metaphysical considerations of immune cell epigenetic reprogramming obtaining biochemical event ontologies. DJGPhD.23.6.23. Authentic Biochemistry Podcast

References

Guerra: logical propositions and dialectical syntheses

Annual Review of Immunology2021. Volume 39: 279-311

2 years, 11 months ago

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ImmunoEpigenetics82.Innate lymphoid progenitor antibody-directed single cell DNAse hypersenitive site analysis of transcription factor specific histone methylation and acetylation modifications.DJGPhD
ImmunoEpigenetics82.Innate lymphoid progenitor antibody-directed single cell DNAse hypersenitive site analysis of transcription factor specific histone methylation and acetylation modifications.DJGPhD

References

Nat Protoc. 2017 Nov;12(11):2342-2354

Annual Review of Immunology 2021. Volume 39. pp 279-311

Immunity 2022. Volume 55, Issue 8. Pages 14…

2 years, 11 months ago

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ImmunoEpigenetics 81.Innate lymphoid cells lack antigen receptors and are differentiated into multiple linneages via epigenetic priming of nucleosomal regions proximal to cell-specific TF's.DJGPhD.
ImmunoEpigenetics 81.Innate lymphoid cells lack antigen receptors and are differentiated into multiple linneages via epigenetic priming of nucleosomal regions proximal to cell-specific TF's.DJGPhD.

References

Immunity 2022. 55, Issue 8. Pages 1402-1413.

Methods Mol Biol. 2018;1675:167-181.

Experimental & Molecular Medicine 2019. volume 51, Arti…

2 years, 11 months ago

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ImmunoEpigenetics80.T lymphocyte biochemical communications are triggered epigentically and via membrane lipid molecular species recombination: A dialectical event ontological view. DJGPhD.17.6.23
ImmunoEpigenetics80.T lymphocyte biochemical communications are triggered epigentically and via membrane lipid molecular species recombination: A dialectical event ontological view. DJGPhD.17.6.23

Reference

Authentic Biochemistry Lecture synthesis


2 years, 11 months ago

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ImmunoEpigenetics79. T lymphocyte DPPA induced HSP27 deoligomerization-activating DGK-a associated anergy is linked to cancer cell proliferation phenotypes. DJGPhD.16.6.23b Authentic Biochemistry
ImmunoEpigenetics79. T lymphocyte DPPA induced HSP27 deoligomerization-activating DGK-a associated anergy is linked to cancer cell proliferation phenotypes. DJGPhD.16.6.23b Authentic Biochemistry

Reference

J BiolChem. 2023 Mar; 299(3): 103019.

2 years, 11 months ago

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ImmunoEpigenetics 78. Classical ergodic forward deterministics do not explain biological systems; biochemical phenomena are tuned for uncertain events. DJGPhD.16.6.23. Authentic Biochemistry Podcast
ImmunoEpigenetics 78. Classical ergodic forward deterministics do not explain biological systems; biochemical phenomena are tuned for uncertain events. DJGPhD.16.6.23. Authentic Biochemistry Podcast

References

J Biol Chem 2017 292: 20481.

Critique if Pure Reason.1781. Kant,I.

Guerra,2023. manuscripts in preparation

2 years, 11 months ago

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ImmunoEpigenetics77. T cell membrane phospholipase D mediated PA deprotonation as a biosensor for an electrostatic/hydrogen-bond signal transductionDJGPhD.15.6.23. Authentic Biochemistry Podcast.
ImmunoEpigenetics77. T cell membrane phospholipase D mediated PA deprotonation as a biosensor for an electrostatic/hydrogen-bond signal transductionDJGPhD.15.6.23. Authentic Biochemistry Podcast.

References

The Journal of Biological Chemistry 2007.282,11356-11364.

BMC Biology 2011. 9:85

Cancer Res . 2011 Jan 15;71(2):293-7.

J BiolChem. 2023 Ma…

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Interum lecture VI. Entropic forces and the ergodic hierarchy of GPCR-linked phsopholipase phase space postioning temporality. DJGPhD.13.6.23
Interum lecture VI. Entropic forces and the ergodic hierarchy of GPCR-linked phsopholipase phase space postioning temporality. DJGPhD.13.6.23

References

ACS Omega. 2019 Nov 26; 4(22):19526–19547

Guerra: general thermodynamics lectures

2 years, 11 months ago

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Interum Lecture V. Semi-closure on free energy and enthalpic involvement in leptin/AMPK mediated orexigenic states . DJGPhD.12June23.Authentic Biochemistry Podcast
Interum Lecture V. Semi-closure on free energy and enthalpic involvement in leptin/AMPK mediated orexigenic states . DJGPhD.12June23.Authentic Biochemistry Podcast

Reference

Guerra lecture material

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