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ImmunoEpigenetics84. T cell and ILC transcription factor and cytokine signaling coordination to accelerate a combined innate/acquired immune response requires discrete epigenetic programming. DJGPhD.
References
J Exp Med. 2017 Jul 3;214(7):1861-1876
Immunol Rev. 2014 Sep;261(1):62-83
Int J Mol Sci. 2022 Mar; 23(5): 2878.
Immunity 2022. Volume 55,…
2 years, 11 months ago
ImmunoEpigenetics 83. Epistemic and metaphysical considerations of immune cell epigenetic reprogramming obtaining biochemical event ontologies. DJGPhD.23.6.23. Authentic Biochemistry Podcast
References
Guerra: logical propositions and dialectical syntheses
Annual Review of Immunology2021. Volume 39: 279-311
2 years, 11 months ago
ImmunoEpigenetics82.Innate lymphoid progenitor antibody-directed single cell DNAse hypersenitive site analysis of transcription factor specific histone methylation and acetylation modifications.DJGPhD
References
Nat Protoc. 2017 Nov;12(11):2342-2354
Annual Review of Immunology 2021. Volume 39. pp 279-311
Immunity 2022. Volume 55, Issue 8. Pages 14…
2 years, 11 months ago
ImmunoEpigenetics 81.Innate lymphoid cells lack antigen receptors and are differentiated into multiple linneages via epigenetic priming of nucleosomal regions proximal to cell-specific TF's.DJGPhD.
References
Immunity 2022. 55, Issue 8. Pages 1402-1413.
Methods Mol Biol. 2018;1675:167-181.
Experimental & Molecular Medicine 2019. volume 51, Arti…
2 years, 11 months ago
ImmunoEpigenetics80.T lymphocyte biochemical communications are triggered epigentically and via membrane lipid molecular species recombination: A dialectical event ontological view. DJGPhD.17.6.23
Reference
Authentic Biochemistry Lecture synthesis
2 years, 11 months ago
ImmunoEpigenetics79. T lymphocyte DPPA induced HSP27 deoligomerization-activating DGK-a associated anergy is linked to cancer cell proliferation phenotypes. DJGPhD.16.6.23b Authentic Biochemistry
Reference
J BiolChem. 2023 Mar; 299(3): 103019.
2 years, 11 months ago
ImmunoEpigenetics 78. Classical ergodic forward deterministics do not explain biological systems; biochemical phenomena are tuned for uncertain events. DJGPhD.16.6.23. Authentic Biochemistry Podcast
References
J Biol Chem 2017 292: 20481.
Critique if Pure Reason.1781. Kant,I.
Guerra,2023. manuscripts in preparation
2 years, 11 months ago
ImmunoEpigenetics77. T cell membrane phospholipase D mediated PA deprotonation as a biosensor for an electrostatic/hydrogen-bond signal transductionDJGPhD.15.6.23. Authentic Biochemistry Podcast.
References
The Journal of Biological Chemistry 2007.282,11356-11364.
BMC Biology 2011. 9:85
Cancer Res . 2011 Jan 15;71(2):293-7.
J BiolChem. 2023 Ma…
2 years, 11 months ago
Interum lecture VI. Entropic forces and the ergodic hierarchy of GPCR-linked phsopholipase phase space postioning temporality. DJGPhD.13.6.23
References
ACS Omega. 2019 Nov 26; 4(22):19526–19547
Guerra: general thermodynamics lectures
2 years, 11 months ago
Interum Lecture V. Semi-closure on free energy and enthalpic involvement in leptin/AMPK mediated orexigenic states . DJGPhD.12June23.Authentic Biochemistry Podcast
Reference
Guerra lecture material
2 years, 11 months ago