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BioMedical Portrait VIII. c.10. The LOX5 and LOX12/15 pathways for 20:4, 20:5 and 22:6produce over 50 unique molecular species of oxylipins and lipoxins with unique biological sequalae.DJGPhD.14.1.24.
References
Int.J. Mol. Sci. 2022, 23(23), 14883.
Prostaglandins Other Lipid Mediators. 2023 Jun:166:106726.
British J of Pharmacology. 2015. Volume17…
2 years, 6 months ago
BioMedical Portrait VIII. c.9. Initial detail of the LOX vs.COX isoform utilization of essential and other dietary PUFA's in complex leukotriene biosynthesis. DJGPhD.11Jan24.Authentic Biochemistry.
References
British J of Pharmacology 2015. Volume172, Issue17September Pages 4319-4330
Prostaglandins Other Lipid Mediators. 2023 Jun:166:106726.
2 years, 6 months ago
BioMedical Portrait vIII. Leukotrienes. c.8 Leukotriene regulated Heterodimer Nuclear Receptor transcription factors organize around complex multi-ligand binding and sojourner molecular modifiers
References
British J of Pharmacology 2015. Volume172, Issue17 September Pages 4319-4330
Chem Rev. 2011 Oct 12; 111(10): 6321–6340
JBiol Chem. 2020 Ju…
2 years, 6 months ago
BioMedical Portrait VIII.c.7. Differential control over fatty acid oxygenation and PPAR/RXR heterodimer pairing in mammalian uterine cell estrus physiology.DJGPhD.8Jan2024
References
General and Comparative Endocrinology,2018-06-01, Volume 262, Pages 27-35
Pisendel JG 1735.Violin Concerto in D major, JunP I.5.
https://y…
2 years, 6 months ago
EtOH Membrane Intoxication c.3. Epiphantei: ethanol-induced membrane degeneration results in altered porosity/tortuosity dynamics and microglia-failed tissue surveilance/repair in the CNS.DJGPhD.
References
Brain Imaging Behav. 2011 Sep; 5(3): 189–202
PLoS One. 2019; 14(1): e0210888.
Alcohol, 2017-12-01, Volume 65, Pages 51-62
Clapton, E. and…
2 years, 6 months ago
EtOH c.2 Mean diffusivity and tortuosity metrics in ethanol induced white matter lesions.
References
PLoS One. 2019; 14(1): e0210888
Trends Neurosci. 2015 Jun; 38(6): 364–374
Addict Biol. 2006 Sep; 11(3-4): 339–355
Sci Rep. 2022; 12: 19463…
2 years, 6 months ago
BioMedical Portrait VIII.c.6 Precursor 20:4 5,8,11,14 derived prostaglandins and leukotriene roles in PPAR and RXR transcription factor expression in mammalian reproductive tissues. DJGPhD. 04JAN24.AB
References
General and Comparative Endocrinology 2018-06-01, Volume 262, Pages 27-35.
Immunohorizons. 2022 Jun 22; 6(6): 366–372.
Biochem J. 2009 Dec…
2 years, 6 months ago
Post Holiday EtOH Lectures. Volume One. Dr. Daniel J. Guerra. 01Jan2024. Authentic Biochemistry
References
Sci Adv. 2020 Jun; 6(26): eaba0154
Brahms , J. 1869 Schicksalslied ∙ hr-Sinfonieorchester.
https://youtu.be/yC8CNpFu_7Q?si=ZqE0nuvXjaRJVcM…
2 years, 6 months ago
BioMedical Portrait VIII.c.5 Leukotrienes. Lipoxygenase isoform mediated control over resident tissue macrophage speciation.Dr Daniel J. Guerra. 01Jan2024. Authentic Biochemistry Podcast
References
Immunohorizons. 2022 Jun 22; 6(6):366–372.
Biochem J. 2009 Dec 14;425(1):265-74
Chem Rev. 2011 Oct 12; 111(10): 6321–6340.
Telemann, Geor…
2 years, 6 months ago
BioMedical Portrait VIII. c.4 A deft-handed apprehension of chirality to facillitate reasoned appreciation of leukotriene molecular heterogeneity.DJGPhD. 30.12.23. Authentic Biochemistry.
References
Dr Guerra-notes
Schubert. F. 1815 (late March-Early April. Stringt Quartet No. 9 in G minor (D.173)
https://youtu.be/piIet7QVLGA?si=FcY0VU…
2 years, 6 months ago