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BioMedical Portrait VI c.6.Hemophagocytic lymphohistiocytosis ACAD9/Rab27A/+/- FBase1 mutations linked to NK and CTL immunodeficiences.DJGPhD. 16/11/23. Authentic Biochemistry.
References
Front Immunol. 2023; 14: 1151166.
Int J Mol Sci. 2019 Jan; 20(2): 443.
2 years, 6 months ago
BioMed Portrait VIc.5. NK cell Inborn Error Of Immunity links to failed fatty acyl CoA dehydrogenase-obtained immunodeficiency.DJGPhD. 15.11.23. Authentic Biochemistry
References
Front Immunol. 2023; 14: 1151166
2 years, 6 months ago
BioMedical Portrait VI.c4. Tumor and DC antigen VAX directed melanoma therapy reveals CD8+CTL and NK cell surface population dynamics.DJGPhG.14.11.23. Authentic Biochemistry.
References
Cancers 2020, 12(4),952
JBC. 2018. 293: 2422-2437.
J Immunother Cancer. 2021 Nov;9(11):e003675
Front Oncol. 2023 May 18:13:1145667
Front. …
2 years, 6 months ago
BioMedical PortraitVIc.3. NK cell phenotypic variation is tighly regulated to facillitate unique immune sequalae including tumor ablation, pathogen elimination and autoimmunity.13.11.23.DJGPhD
References
Immunity. 2018 Oct 16;49(4):695-708
Front Immunol. 2019; 10: 14
Front. Immunol., 24 July 2017 Vol 8. Sec. T Cell Biology
2 years, 6 months ago
BioMedical ortrait VI. Development of a dendritic cell antigen presenting melanoma kinase derived vax targeting NK cells to ablate malignancy.DJGPhD.11NOV23
References
Front Immunol. 2019; 10: 14
Cancer Immunol Immunother. 2016 Apr;65(4):441-52
Anal Cell Pathol (Amst).2018; 2018: 787.1814.
Molecular Cance…
2 years, 6 months ago
BioMedical Potrait VI. Natural Killer Cells: opening remarks. DJGPhD.9NOV23. Authentic Biochemistry
References
Anal Cell Pathol (Amst).2018; 2018: 787.1814
Zeno (the Eleatic) 5thCentury B.C. Magna Graecia, Italian Penn. Student of Parmenides
Guerra-…
2 years, 6 months ago
BioMedical Portrait V. Coda c.13 Small molecule pyrazolo-oxazepine derivitive mediated PFK-1 activation depletes NADPH dependent neutrophil oxidative burst. DJGPhD.07NOV23. Authentic Biochemistry
References
Cell 2021. 184, 1–15
J Zhejiang Univ Sci B. 2022 Jul 15; 23(7): 607–612.
2 years, 6 months ago
BioMedical Portrait V.c.12. Is there a compositional-sequential event ontology linking "moonlighting"c-Fos with NOX2 PX domain PIP3 binding?DJGPhD. 6NOV23
References
Nature Communications 2019. volume 10, Article number: 1528
Adv Exp Med Biol. 2019:1111:1-17. doi10.1007/5584_2018_185.
Nature Immunology…
2 years, 6 months ago
BioMedical Portrait V.c.11 The Phosphoglycerolipid metabolome that orchestrates membrane topology and surface chemistry that supports necessary protein association for neutrophil immunoresponses.
References Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids2014.Volume 1841, Issue 9, Pages 1241-1246 Guerra-graduate lipid…
2 years, 6 months ago
BioMedical Portrait V.c.10. Phosphphatidyl inositols and phagosmal genesis in activated neutrophils upon pathogen infection.
References
J Adv Res. 2018 May; 11: 33–41.
Immunol Rev. 2023. Volume314, Issue1 .Special Issue: Neutrophils and Friends.March 2023. Pages 158-180.
B…
2 years, 6 months ago