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Biochemical Mosaic II. c.3 Plasmalogen metabolism is coherently associated with peroxisomal integrity and replication. DJGPhD.01March 2024 Authentic Biochemistry.
References
Oncol Lett. 2018 May; 15(5): 7889–7899
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Biochim Biophys Acta Mol Cell Res. 2020 Feb;1867(2):118609
Protein…
2 years, 4 months ago
Biochemical Mosaic II. C.2. Plasmalogen and PAF biosynthesis in relation to glycerol lipid and intermediary subcellular metabolism.DJGPhD.27.2.24
References
Guerra: graduate biochemistry lectures
Chopin, F. 1830. Nocturne E Flat Major Op.9 No.2
https://youtu.be/tV5U8kVYS88?si=MKxfguVRI6hhQeMO
W…
2 years, 4 months ago
Biochemical Mosaic II. Plasmalogens & other ether lipids. c.1 DJGPhD.26.2.24. Authentic Biochemistry Podcast
References
Cell Metab. 2014 Mar 4; 19(3): 380–392.
Protein Cell 2018. 9, 196–206.
Membranes 2023, 13(9), 764.
Debussy , C. (. 1890;1905) Clair de l…
2 years, 4 months ago
A Dialectical Interlocution with Mozart. DJGPhD.24.2.24 Authentic Biochemistry Podcast
References
Mozart.WA
1782. Fantasie in D minor. K.397
https://youtu.be/OYiz_u0tDwM?si=0dP736rTEkb4sauL
1785.Piano Concerto 22 in E flat Major.K.482
h…
2 years, 4 months ago
Biochemical Mosaic I. CODA. Membrane lipids function as biosensors for pKa's of phosphonoester anionic charge density with polybasic protein domains to mediate communication including transcription.
References
J Biol Chem 2017 292: 20481.
Nature Cell Biology 2019. volume 21, pages 338–347
Rossini.G. 1829. William Tell Overture.
https://youtu.be/…
2 years, 4 months ago
Biochemical MosaicI.c.13 Phosphatidic acid as key lipid intermediary of membrane secretion signalling and cellular intracommunication via kinase cascade and transcriptional regulation.DJGPhD.22.2.24
References
Biomedicines 2023, 11(7), 1804
BMC Biology. 2011. 9:85
Cancer Res. 2011 Jan 15;71(2):293-7.
FEBS Lett.2019.593.17:2428-2451
Verdi, G. 184…
2 years, 5 months ago
Biochemical Mosaic I. c.12. The porosomal secretory system requires anioic lipids including phosphatidic acid. DJGPhD.21.2.24
Dr. Guerra: membrane graduate biochemistry lecture notes
J Cell Mol Med . 2015 Jul;19(7):1427-40
Langmuir, 2018, 34 (1), pp 530–539
Elgar, E. 1900. T…
2 years, 5 months ago
Biochemical Mosaic I.c.11. Glycerolipid metabolism coupled to mTORC1 enzyme phosphorylation necessarily involves a complete analysis of membrane lipid molecular species distribution.DJGPhD.20.2.24
References
Nature . 2019 Nov;575(7782):361-365.
Adv Biol Regul. 2017 May:64:39-48
J Biol Chem. 2013 Apr 5; 288(14): 9933–9945
Redox Biology.2017. V…
2 years, 5 months ago
Biochemical Mosaic I c.10. Is PE depletion reversed by mTORC1 phosphorylation of LIPIN1 or is DAG authentically activating CCT via membrane association thus obtaining robust PL synthesis? DJGPhD.
References
Biochim Biophys Acta. 2011 Jun;1811(6):377-85
Am J Physiol Lung Cell Mol Physiol 2001. 281: L98–L107.
Biochimica et Biophysica Acta…
2 years, 5 months ago
Biochemical Mosaic I. c.9 Increased inner mitochondrial membrane PE from PS decarboxylase decreases protease mediated degradation of phospholipid transfer proteins thus maintaining fusion potency.
References
PLoS Biol 2014. 12(10): e1001969
J Biol Chem. 2012 May18;287(21):17589-17597
J Biol Chem. 2012 Nov 23;287(48):40131-9
Nature 2019. volume …
2 years, 5 months ago