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BioMedical Portrait VIII.c.15. ILC associated hippocampal RNA-BP's exacerbate GLU neurotoxicity and regulate CysLT1R in lung ILC2's. DJGPhD. 23.1.24.
References
Nat Commun. 2022; 13: 4435.
Nat Commun 2020; 11: 35
Hayward, J. 1971. "You Can Never Go Home" Moody Blues.
https://youtu.be/mUhboF8d1x0?…
2 years, 4 months ago
BioMedical Portrait VIII.c.14 The dialectical events between immune responses and leukotriene signaling are modulated by tissue-resident and circulating cell patterns via RNA binding proteins.DJGPhD.
References
Nat Commun. 2022; 13: 4435.
Virchows Archiv: European Journal of Pathology, 2020. Vol. 476, Issue 2
Cell Death Differ. 2015 Apr; 22(5): 7…
2 years, 4 months ago
BioMedical PortraitVIII.c.13 Leukotriene metabolism and reception is linked to innate like lymphocytes involved in airway inflammation and hyper-responsiveness-associated asthma.DJGPhD.19.1.24.AB.
References
J Immunol. 2009 Feb 1; 182(3): 1641–1647. Cell Reports 2015 10, 2043-2054DOI
Virchows Archiv:European Journal of Pathology. 2020. 09456317…
2 years, 4 months ago
BioMedical Portrait VIII.c.12. 5-LOX associates with FLAP and PLA2 at the nuclear envelope to trigger and control ILC2 mediation of the allergic asthma AHR pathology. DJGPhD 17.1.24. Authentic Bioch.
References
Immunology. 2019 Apr; 156(4): 402–412.
J Immunol. 2017 Aug 1; 199(3): 1096–1104
Front. Immunol., 06 June 2019
Mol Biol Cell. 2012 Nov 15;…
2 years, 4 months ago
BioMedical Portrait VIII. C.11 Peptidyl leukotrieneR- mediated transcription of PTGS2and LOX15B with IL4/IL13 and IL33 in asthmatic lung airway constrictionin MDM's LM's and ILC2's DJGPhD.16.1.24
References
Immunol.2017 Aug 1; 199(3): 1096–1104.
British J of Pharmacology. 2015. Volume172, Issue17: 4319-4330
Beethoven, L. 1826. String Quartet O…
2 years, 4 months ago
BioMedical Portrait VIII. c.10. The LOX5 and LOX12/15 pathways for 20:4, 20:5 and 22:6produce over 50 unique molecular species of oxylipins and lipoxins with unique biological sequalae.DJGPhD.14.1.24.
References
Int.J. Mol. Sci. 2022, 23(23), 14883.
Prostaglandins Other Lipid Mediators. 2023 Jun:166:106726.
British J of Pharmacology. 2015. Volume17…
2 years, 4 months ago
BioMedical Portrait VIII. c.9. Initial detail of the LOX vs.COX isoform utilization of essential and other dietary PUFA's in complex leukotriene biosynthesis. DJGPhD.11Jan24.Authentic Biochemistry.
References
British J of Pharmacology 2015. Volume172, Issue17September Pages 4319-4330
Prostaglandins Other Lipid Mediators. 2023 Jun:166:106726.
2 years, 4 months ago
BioMedical Portrait vIII. Leukotrienes. c.8 Leukotriene regulated Heterodimer Nuclear Receptor transcription factors organize around complex multi-ligand binding and sojourner molecular modifiers
References
British J of Pharmacology 2015. Volume172, Issue17 September Pages 4319-4330
Chem Rev. 2011 Oct 12; 111(10): 6321–6340
JBiol Chem. 2020 Ju…
2 years, 4 months ago
BioMedical Portrait VIII.c.7. Differential control over fatty acid oxygenation and PPAR/RXR heterodimer pairing in mammalian uterine cell estrus physiology.DJGPhD.8Jan2024
References
General and Comparative Endocrinology,2018-06-01, Volume 262, Pages 27-35
Pisendel JG 1735.Violin Concerto in D major, JunP I.5.
https://y…
2 years, 4 months ago
EtOH Membrane Intoxication c.3. Epiphantei: ethanol-induced membrane degeneration results in altered porosity/tortuosity dynamics and microglia-failed tissue surveilance/repair in the CNS.DJGPhD.
References
Brain Imaging Behav. 2011 Sep; 5(3): 189–202
PLoS One. 2019; 14(1): e0210888.
Alcohol, 2017-12-01, Volume 65, Pages 51-62
Clapton, E. and…
2 years, 4 months ago