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Menopause, Part 1: What It Actually Is and the 24-Year WHI Correction
Menopause, Part 1: What It Actually Is and the 24-Year WHI Correction

Episode 400

In 1889 a French physiologist injected himself with guinea pig and dog testicle extract and published a claim of self-rejuvenation in The Lancet. Tha…

5 months ago

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Is Creatine Causing Your Shin Pain? + Splitting Training, Endometriosis for Lifters | Direct Line · May 2026
Is Creatine Causing Your Shin Pain? + Splitting Training, Endometriosis for Lifters | Direct Line · May 2026

Episode 399

This is the free preview of the May 2026 Direct Line, our monthly AMA for Barbell Medicine Plus subscribers. Three reader questions answered in full.…

5 months, 2 weeks ago

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What’s Actually Driving Your Testosterone Down? | Signal Ep 3
What’s Actually Driving Your Testosterone Down? | Signal Ep 3


Most cases of low testosterone in modern men are not a problem with the testes. The number is downstream of body composition, sleep, and energy avail…

5 months, 3 weeks ago

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Progressive Loading Part 3: Why the Novice / Intermediate / Advanced Framework Doesn't Work, and What to Do Instead
Progressive Loading Part 3: Why the Novice / Intermediate / Advanced Framework Doesn't Work, and What to Do Instead

Episode 397

Three weeks of stalled squats. The conventional answer is to switch programs because you've crossed into intermediate territory. The data says someth…

5 months, 4 weeks ago

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Is Your Testosterone Actually Low? Why Higher Testosterone Doesn't Do What You Think | Signal Ep 2
Is Your Testosterone Actually Low? Why Higher Testosterone Doesn't Do What You Think | Signal Ep 2

Out of 32 symptoms commonly attributed to low testosterone, only 3 actually correlate with it. All three are sexual. The other 29 — fatigue, brain fo…

6 months, 1 week ago

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Direct Line April 2026: Stopping Ozempic and Lifting With Osteopenia
Direct Line April 2026: Stopping Ozempic and Lifting With Osteopenia

Episode 395

Stop a GLP-1 and about two thirds of the weight loss comes back within a year. Three randomized withdrawal trials (SURMOUNT-4, STEP 1 extension, STEP…

6 months, 2 weeks ago

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Is the Testosterone Crisis Real? The Numbers Behind the Headlines | Signal Ep 1
Is the Testosterone Crisis Real? The Numbers Behind the Headlines | Signal Ep 1

Episode 394

Every week there's a new headline saying men are losing testosterone. A quarter of men now start testosterone replacement therapy without ever gettin…

6 months, 3 weeks ago

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Medical Mystery: The Man Who Got Weaker When He Started Training
Medical Mystery: The Man Who Got Weaker When He Started Training

Episode 393

A 43-year-old man starts exercising and ends up in the ER with a CK over 100x the upper limit of normal. His doctor says it’s from training. We don’t…

6 months, 4 weeks ago

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Overtraining Syndrome: Causes, Diagnosis, and What's Actually Going On
Overtraining Syndrome: Causes, Diagnosis, and What's Actually Going On

Episode 392

In 2022, researchers conducted the most rigorous systematic review ever performed on overtraining syndrome — looking specifically for controlled stud…

7 months ago

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Episode #391: VO2 Max vs. Cardiorespiratory Fitness, GLP-1 Costs, and the 10,000-Step Myth | Direct Line March 2026 (Free)
Episode #391: VO2 Max vs. Cardiorespiratory Fitness, GLP-1 Costs, and the 10,000-Step Myth | Direct Line March 2026 (Free)

In this free preview of the March 2026 Direct Line AMA. Drs. Feigenbaum and Baraki cover: VO2 max versus cardiorespiratory fitness for longevity (are…

7 months, 1 week ago

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