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Do You Need a Calorie Surplus to Build Muscle? | Dr. Eric Helms
Do You Need a Calorie Surplus to Build Muscle? | Dr. Eric Helms

Episode 415

Most lifters have been told they need to eat in a Calorie surplus to build muscle. That rule has always come with a list of exceptions: unless you're…

20 hours ago

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Is Obesity A Muscle Problem?
Is Obesity A Muscle Problem?

Episode 414

Muscle is where most of the glucose goes, and muscle insulin resistance is the first thing that breaks on the road to type 2 diabetes. Both of those …

2 weeks ago

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Who Needs Testosterone, and Who's Not Getting It I Signal Episode 4
Who Needs Testosterone, and Who's Not Getting It I Signal Episode 4

Episode 413

Most men who start testosterone never needed it, and some who genuinely do never get treated. In the final episode of the Signal series, Dr. Jordan F…

3 weeks, 1 day ago

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Your Fat Has a Storage Limit
Your Fat Has a Storage Limit

Episode 412

In 2004 a surgeon removed about ten kilograms of fat from fifteen women and measured everything that mattered. Nothing improved. Four years later, it…

4 weeks, 1 day ago

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Lifting and longevity: is 1 hour a week really the limit? Plus GLP1s and mood, training with ME/CFS, and Protein vs. Calories
Lifting and longevity: is 1 hour a week really the limit? Plus GLP1s and mood, training with ME/CFS, and Protein vs. Calories

Episode 411

A popular paper claimed the longevity benefit of lifting disappears once you train more than an hour a week. It's a real paper, but the claim is a mi…

1 month ago

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The FDA Voted for 6 Peptides. Its Own Scientists Said No
The FDA Voted for 6 Peptides. Its Own Scientists Said No

Episode 410

An FDA advisory committee just voted to open a legal compounding supply line for six of seven peptides, including BPC-157 and TB-500, over the object…

1 month, 1 week ago

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The Man Who Couldn’t Stop Gaining Weight | A Medical Mystery
The Man Who Couldn’t Stop Gaining Weight | A Medical Mystery

Episode 409

A previously healthy 21-year-old shows up with seven months of headaches and 30-plus pounds of weight gain he can’t explain. He’s eating the same and…

1 month, 2 weeks ago

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The Protein Scaries: What the Research Says About Your Kidneys, Cancer, Bones, and Body Fat
The Protein Scaries: What the Research Says About Your Kidneys, Cancer, Bones, and Body Fat

Episode 407

Every couple of years a new headline warns that the protein you eat is quietly hurting you. This year the target is your kidneys. Before that it was …

1 month, 3 weeks ago

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Is It Really Just Calories In, Calories Out? Metabolism, Insulin, Hormones and Why Counting Fails
Is It Really Just Calories In, Calories Out? Metabolism, Insulin, Hormones and Why Counting Fails

Episode 406

Is weight loss really just Calories in, Calories out? The equation is true, but "just count your Calories" is bad advice for most people, and almost …

2 months ago

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Is Obesity a Willpower Problem? The Biology of Weight, Diets, and GLP-1s
Is Obesity a Willpower Problem? The Biology of Weight, Diets, and GLP-1s

Episode 405

Obesity roughly tripled in about 60 years, and the genes didn't change in that time. So if body weight isn't a willpower problem, what is it? Dr. Jor…

2 months, 1 week ago

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