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Biochemical Mosaic II.c.6 Meduloblastoma is linked to plasmalogen and circ RNA phenomena that are pathophenocopied in other cancers. DJGPhD.5.Mar24.Authentic Biochemistry
References
Acta Neuropathologica Communications 2023. volume 11, Article number: 38
Proc Natl Acad Sci U S A. 2020 Apr 7; 117(14): 7792–7798.
Int J …
2 years, 2 months ago
Biochemical Mosaic II. c.5 Peroxisomal plasmalogen biosynthesis may regulate transcriptomic and proteomic sequalae to plasmamembrane mediated signal transduction. DJGPhD.4March24.
References
Front Physiol. 2021; 12: 730829.
Non-coding RNA Investig 2017. 1:5.
Genome Biology 2011. volume 12, Article number: 236
RNA Biol . 2021 …
2 years, 2 months ago
Biochemical Mosaic II. c.4. Peroxisomal biogenesis and AGPS-mediated plasmalogen synthesis involve circular RNA species that alter microRNA and mRNA expression in human cancers. DJGPhD.3MAR24.
References
Genome Res. 2004 Nov;14(11): 2245–2252.
Int J Med Sci. 2022; 19(6): 975–985.
Oncol Lett. 2018 May; 15(5): 7889–7899.
Cell Death Dis. 20…
2 years, 2 months ago
Saturday Night Authentic Biochemistry The Agentic operator as metaphysical metaphor in metabolic regulation. DJGPhD.2March 2024.
References
Dr Guerra Archives: Graduate Biochemistry Lecture notes and syntheses
Simon, P. 1969. The Boxer.
https://youtu.be/l3LFML_pxlY?si=Nv5-mSzR…
2 years, 2 months ago
Biochemical Mosaic II. c.3 Plasmalogen metabolism is coherently associated with peroxisomal integrity and replication. DJGPhD.01March 2024 Authentic Biochemistry.
References
Oncol Lett. 2018 May; 15(5): 7889–7899
Nat Genet. 1997 Apr;15(4):369-76
Biochim Biophys Acta Mol Cell Res. 2020 Feb;1867(2):118609
Protein…
2 years, 2 months ago
Biochemical Mosaic II. C.2. Plasmalogen and PAF biosynthesis in relation to glycerol lipid and intermediary subcellular metabolism.DJGPhD.27.2.24
References
Guerra: graduate biochemistry lectures
Chopin, F. 1830. Nocturne E Flat Major Op.9 No.2
https://youtu.be/tV5U8kVYS88?si=MKxfguVRI6hhQeMO
W…
2 years, 2 months ago
Biochemical Mosaic II. Plasmalogens & other ether lipids. c.1 DJGPhD.26.2.24. Authentic Biochemistry Podcast
References
Cell Metab. 2014 Mar 4; 19(3): 380–392.
Protein Cell 2018. 9, 196–206.
Membranes 2023, 13(9), 764.
Debussy , C. (. 1890;1905) Clair de l…
2 years, 2 months ago
A Dialectical Interlocution with Mozart. DJGPhD.24.2.24 Authentic Biochemistry Podcast
References
Mozart.WA
1782. Fantasie in D minor. K.397
https://youtu.be/OYiz_u0tDwM?si=0dP736rTEkb4sauL
1785.Piano Concerto 22 in E flat Major.K.482
h…
2 years, 3 months ago
Biochemical Mosaic I. CODA. Membrane lipids function as biosensors for pKa's of phosphonoester anionic charge density with polybasic protein domains to mediate communication including transcription.
References
J Biol Chem 2017 292: 20481.
Nature Cell Biology 2019. volume 21, pages 338–347
Rossini.G. 1829. William Tell Overture.
https://youtu.be/…
2 years, 3 months ago
Biochemical MosaicI.c.13 Phosphatidic acid as key lipid intermediary of membrane secretion signalling and cellular intracommunication via kinase cascade and transcriptional regulation.DJGPhD.22.2.24
References
Biomedicines 2023, 11(7), 1804
BMC Biology. 2011. 9:85
Cancer Res. 2011 Jan 15;71(2):293-7.
FEBS Lett.2019.593.17:2428-2451
Verdi, G. 184…
2 years, 3 months ago