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Biochemical Mosaic III c.3. Bacterial glycosphingolipid mediated inflammasome activation and the Galectin:NLRP3 interaction pathophenocopy oxy-mtDNA TLR induction.DJGPhD.21.3.24
Biochemical Mosaic III c.3. Bacterial glycosphingolipid mediated inflammasome activation and the Galectin:NLRP3 interaction pathophenocopy oxy-mtDNA TLR induction.DJGPhD.21.3.24

References

Front Immunol. 2020; 11: 591803

Am J Gastroenterol. 2004 Nov;99(11):2147-9.

Biochem Biophys Res Commun. 2005 Dec 16;338(2):1031-6

Front Im…

2 years, 2 months ago

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Biochemical Mosaic III. C.2 A Non-canonical autophagic inhibition of NLRP3 inflammasome mediated inflammation in UVB-treated human keratinocytes.DJGPhD. 20.3.24.
Biochemical Mosaic III. C.2 A Non-canonical autophagic inhibition of NLRP3 inflammasome mediated inflammation in UVB-treated human keratinocytes.DJGPhD. 20.3.24.

References

Front Immunol. 2019 Jun 7;10:1309.

JBC 2024 . March.Article in Press
DOI:https://doi.org/10.1016/j.jbc.2024.107173

FASEB J. 2016 Dec;30(12…

2 years, 2 months ago

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Biochemical Mosaic III. C.1. Inflammasomes. DJGPhD.19.3.24 Authentic Biochemistry Podcast
Biochemical Mosaic III. C.1. Inflammasomes. DJGPhD.19.3.24 Authentic Biochemistry Podcast

References

Immunity 2022. Volume 55 Issue 8 Pages 1370-1385.e8

JBC 2024. March. Article in Press

https://doi.org/10.1016/j.jbc.2024.107173

Schmelze…

2 years, 2 months ago

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Biochemical MosaicII.Book2.C.13.Dialectical event ontologies involving CNS plasmalogen and sphingolipid interlocution and the universality of Mozart and the Beatles. DJGPhD.17.3.24.Authentic Biochem.
Biochemical MosaicII.Book2.C.13.Dialectical event ontologies involving CNS plasmalogen and sphingolipid interlocution and the universality of Mozart and the Beatles. DJGPhD.17.3.24.Authentic Biochem.

REferences

Dr. Guerra. 2024.Previous Authentic Biochemistry Mosaic II lectures in the series

Kant, I. 1790. Critique of Judgment.

Mozart, WA. 1788. …

2 years, 2 months ago

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Biochemical Mosaic II.Book 2. c.12 Adduced mTORC mediated glycerol-sphingolipid enzyme mRNA transcriptome association with Plasmalogen apodiction of myelination.DJGPhD.16.3.24
Biochemical Mosaic II.Book 2. c.12 Adduced mTORC mediated glycerol-sphingolipid enzyme mRNA transcriptome association with Plasmalogen apodiction of myelination.DJGPhD.16.3.24

References

Developmental Cell 2022. Volume 57, Issue 6, 28 March Pages 691-706

Cell Rep. 2014 Feb 13; 6(3): 541–552.

Dr Guerra: graduate lecture not…

2 years, 2 months ago

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MosaicII,Bk.2.c.11 Squalene monooxygenase (SM) stabilization due to plasmalogen pathway fatty acid reductase deficiency promotes SM epoxidase alternate activity thus lowering24OHCHOL-LXR-myelination.
MosaicII,Bk.2.c.11 Squalene monooxygenase (SM) stabilization due to plasmalogen pathway fatty acid reductase deficiency promotes SM epoxidase alternate activity thus lowering24OHCHOL-LXR-myelination.

References

Dr Guerra-Graduate lipid biochemistry lectures

Biochem J. 2022 Sep 30; 479(18): 1917–1940

Front Cell Dev Biol. 2022; 10: 946393.

Nat Comm…

2 years, 2 months ago

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Biochemical Mosaic II. Book2. c.10.Plasmalogen mediated oxy vs epoxy sterol synthesis may control cns inflammation and myelination given acid-catalyzed transacetalization sequalae.DJGPhD.12March24
Biochemical Mosaic II. Book2. c.10.Plasmalogen mediated oxy vs epoxy sterol synthesis may control cns inflammation and myelination given acid-catalyzed transacetalization sequalae.DJGPhD.12March24

References

Front Cell Dev Biol. 2022; 10: 946393.

Adv Exp Med Biol. 2024:1440:149-161

Mozart, WA..1786.Horn Concerto in E-flat major # 4 KV 495

htt…

2 years, 2 months ago

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Biochemical Mosaic II. Book2. c.9. Plasmalogen regulation of composite ruling over prescriptive organization of cellular-biochemical phenomena includes florid mediation of the CNS.DJGPhD.11MARCH2024.
Biochemical Mosaic II. Book2. c.9. Plasmalogen regulation of composite ruling over prescriptive organization of cellular-biochemical phenomena includes florid mediation of the CNS.DJGPhD.11MARCH2024.

References

Journal of Cell Science 2019.Vol.132(6), 223016.

Brain Research Bulletin 2023.Volume 194, March. Pages 118-123.

Beethoven, LV. 1806. Violi…

2 years, 2 months ago

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Biochemical Mosaic II.c.8 Cell death and CE-circ RNA vs.miRNA in Hepatocellular carcinoma: the spectre of AGPS et al. DJGPhD. 10March24.Authentic Biochemistry.
Biochemical Mosaic II.c.8 Cell death and CE-circ RNA vs.miRNA in Hepatocellular carcinoma: the spectre of AGPS et al. DJGPhD. 10March24.Authentic Biochemistry.

References

Cell Death Dis. 2020 Dec; 11(12): 1065.

Genome Res. 2000 Oct; 10(10): 1445–1452.

https://www.genecards.org/cgi-bin/carddisp.pl?gene=NIPB…

2 years, 2 months ago

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Biochemical Mosaic II.c.7. Fatty acid desaturation and mole% PC/PE/PL/CER are elevated via circRNA in Medublastoma while AGPS increased circRNA's in thyroid cancer.DJGPhD.7Mar24. Authentic Biochem.
Biochemical Mosaic II.c.7. Fatty acid desaturation and mole% PC/PE/PL/CER are elevated via circRNA in Medublastoma while AGPS increased circRNA's in thyroid cancer.DJGPhD.7Mar24. Authentic Biochem.

References

Acta Neuropathologica Communications 2023. volume 11, Article number: 38

Proc Natl Acad Sci U S A. 2020 Apr 7; 117(14): 7792–7798

Front M…

2 years, 2 months ago

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