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147: The Wrong Vitamin E Supplement Can Hurt You



In this conversation, Dr. Barrie Tan joins Dr. Buck Joffrey to discuss the significance of tocotrienols—a lesser-known form of vitamin E—and their potential role in preventing chronic disease and pro…


Published on 2 months, 1 week ago

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146: AMA President Dr. Bobby Mukkamala - Healthspan-Centric Medical Care in America



Joining Dr. Buck Joffrey this week, Dr. Bobby Mukkamala shares his journey from aspiring cardiothoracic surgeon to becoming the president of the American Medical Association. He discusses his persona…


Published on 2 months, 2 weeks ago

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145: Why Some Animals Live Longer Than Others with Dr. Steven Austad



In this conversation, Dr. Buck Joffrey and Dr. Steven Austad discusse the biology of aging, the evolutionary aspects of longevity, and the potential for genetic technologies to extend human health sp…


Published on 2 months, 3 weeks ago

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144: Why the Brain is Especially Vulnerable to Aging



In this conversation, Dr. Buck Joffrey and Dr. Julie Andersen explore the molecular mechanisms behind neurodegenerative diseases, with a particular focus on the aging brain.

They discuss the brain’s …


Published on 2 months, 4 weeks ago

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143: The Longevity Dividend with Prof. Jay Olshansky



In this conversation, Professor S. Jay Olshansky discusses the evolution of aging science, the realistic limits of human life expectancy, and the concept of the Longevity Dividend, which emphasizes t…


Published on 3 months ago

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142: The Gut-Muscle Axis with Dr. Michael Lustgarten



In this episode, Dr. Michael Lustgarten discusses his research on the gut microbiome, serum metabolome, and muscle health in older adults. He shares insights from his journey into the world of agi…


Published on 3 months, 1 week ago

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141: A Thermostat for Your Body Fat



In this conversation, Dr. Stephan J. Guyenet joins Dr. Buck Joffrey to discuss the complex mechanisms of body fat regulation, focusing on the role of the lipostat and leptin. He explains how the body…


Published on 3 months, 2 weeks ago

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140: Inside the Inflammatory Clock - Measuring and Reversing Biological Age with Dr. David Furman



Dr. David Furman and Dr. Buck Joffrey discuss the complexities of immune aging, the role of inflammation in age-related diseases, and how artificial intelligence is being utilized to enhance research…


Published on 3 months, 3 weeks ago

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139: Rebuilding the Aging Brain - The Role of Neural Stem Cells



In this conversation, Dr. Tara Walker discusses the fascinating topic of adult neurogenesis, the brain's ability to produce new neurons throughout life.

She explains how this process is crucial for c…


Published on 4 months ago

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138: Sleep Impact on Longevity and Health with The Sleep Doctor



Sleep is the secret weapon for a longer, healthier life—and Dr. Michael Breus is here to show you how to use it.

In this episode of Longevity Roadmap, Buck Joffrey dives deep into the science of slee…


Published on 4 months, 1 week ago





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