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BioMedical Portrait III. c10. Ribosomal collision frequency is attenuated by ZAK and GCN2 via mutually exclusive signalling events, DJGPhD. 25.9.23. Authentic Biochemistry Podcast
References
Cell. 2020 Jul 23; 182(2):404–416.e14.
Curr Genet. 2021 Feb; 67(1): 19–26.
RNA Biol. 2023; 20(1): 737–749. published online 13sept23
2 years, 7 months ago
BioMedical Portrait III. c9. Amino acid deprivation-linked fall of polypeptide synthetic fidelity triggers downstream ribosomal stress response phenomena including kinase mediated cell fate sequalae.
References
Cell. 2020 Jul 23; 182(2):404–416.e14.
Nature Communications 2020. volume 11,3146
Curr Genet. 2021 Feb; 67(1):19–26
2 years, 8 months ago
BioMedical Portrait III. c8. Unique mRNA upstream open reading frames direct both the integrated stress response and rare selective up-regulation of stress-correcting protein synthesis.DJGPhD.21.9.23
References
Dr Guerra's lectures
RNA Biol. 2023; 20(1): 737–749
2 years, 8 months ago
BioMedical Portrait III.c.7 Elementary polypeptide synthesis-translation. Lecture 1. DJGPhD.20.9.23.Authentic Biochemistry Podcast.
Reference
Dr Guerra's lecture notes
2 years, 8 months ago
BioMedical Portrait III. c6. Adipokine and the succinate receptor systems in obese adipose inflammation as regulated by AMPK.DJGPhD.19.9.23. Authentic Biochemistry Podcast
References
Cream 1968 Wheels of Fire
J Neuroinflammation. 2019; 16: 34.
Front Immunol. 2019; 10: 345.
Cell Metabolism 2023. Volume 35 Issue 4. 601-6…
2 years, 8 months ago
BioMedical Portrait III.c.5. Adipokine mediated adipose inflamation is linked to the hypothalamic control over metabolism and systemic inflammation.DJGPhD.18.9.23.Authentic Biochemistry Podcast
References
Prostaglandins Leukot Essent Fatty Acids. 2015 Jul;98:49-55
Int J Biol Sci. 2015; 11(11):1272–1280
Front. Physiol., 01 June 2018
Int. J. …
2 years, 8 months ago
BioMedical Portrait III. c.4. Adipose tissue macrophages express galectin binding proteins which alter immunosuppression and polarization;adipokines mediate the inflammatory response. DJGPhD.17.9.23
References
Luigi Boccherini: Symphony Op. 12 No. 4 in D Minor
JCI Insight. 2016 Nov 17; 1(19): e87748
Front Immunol. 2023; 14: 1149366
Adv Biol Regu…
2 years, 8 months ago
BioMedical Portrait III. Immunometabolic disease 3c.Reactive N and O interconversions in obese adipose exacerbate systemic inflammation. 17.9.23. DJGPhD. Authentic Biochemistry Podcast.
References
Inn Med (Heidelb). 2023 Apr;64(4):313-322.
JBC 2001. Volume 276, Issue 31, August. Pages 28799-28805.
2 years, 8 months ago
BioMedical Portrait III. Immunometabolic disease. The obesity-compromised adipose poise to hyperinflammation. DJGPhD. 15.9.23. Authentic Biochemistry.
References
Schubert, Franz. 1824. March.String Quartet #14 in D minor, D.810
Hypertension. 2002;39:1088–1094
Physiol Rev. 2018 Apr1;98(2):641-665.
2 years, 8 months ago
BioMedical Portrait III. c1. Immuno-metabolic disease. Dr. Daniel J. Guerra. 14.9.23. Authentic Biochemistry Podcast.
References
Schubert. F. 1826. "Ständchen" D.899
Immunol Rev. 2020 May; 295(1): 101–113.
Nat Metab. 2022 Sep;4(9):1202-1213
2 years, 8 months ago