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Beyond Standard Treatment: Exploring Pramipexole in Bipolar Depression

In this episode, we explore pramipexole—a Parkinson's medication—as a promising add-on treatment for treatment-resistant bipolar depression. Could a …

8 months, 1 week ago

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SERT Gene Testing: Separating Hype from Evidence

In this episode, we explore the controversial role of SERT gene testing in predicting SSRI response with Dr. Chris Aiken. Can genetic testing really …

8 months, 2 weeks ago

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The SSRI-Anticoagulant Interaction: Evidence-Based Prescribing Strategies

In this episode, we explore a critical drug interaction: SSRIs combined with anticoagulants increase major bleeding risk by 35-47%. Should age and se…

8 months, 2 weeks ago

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Pharmacogenetic Testing in Psychiatry: Help or Hype?

In this episode, we explore the paradox of pharmacogenetic testing with Dr. Chris Aiken: why do these tests consistently fail in clinical trials desp…

8 months, 3 weeks ago

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Lurasidone: Managing Bipolar Depression with Comorbid Anxiety

In this episode, we explore how Lurasidone at lower doses (20-60 mg/day) effectively treats both depression and anxiety in bipolar I disorder. Why do…

8 months, 4 weeks ago

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GLP-1 Agonists vs. Antipsychotic Weight Gain

In this episode, we explore how GLP-1 agonists—the weight loss medications making headlines everywhere—could revolutionize management of antipsychoti…

9 months ago

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Pharmacogenetics-Guided Dosing: Poor vs. Rapid Metabolizers

In this episode, we explore pharmacogenetics-guided dosing strategies with Dr. Chris Aiken. What if your patient's treatment failure isn't about the …

9 months, 1 week ago

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INTEGRATE Guidelines: Standardizing Schizophrenia Pharmacotherapy

In this episode, we explore the newly published INTEGRATE guidelines—the first truly international algorithm for schizophrenia treatment. Should cloz…

9 months, 2 weeks ago

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Pharmacogenetics: Separating Science from Marketing

In this episode, we explore the practical role of genetic testing in psychiatry with Dr. Chris Aiken. Which genetic tests actually matter in clinical…

9 months, 2 weeks ago

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Lithium vs. Quetiapine: Augmenting Treatment-Resistant Depression

In this episode, we explore a head-to-head comparison of lithium versus quetiapine augmentation for treatment-resistant depression. When patients hav…

9 months, 3 weeks ago

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