Episode Details

I sit down with Len May, co‑founder and CEO of EndoDNA, to unpack what our genetics are really telling us about how we eat, handle stress, and respond to our environment. Len explains DNA as an “encoding” that sets up predispositions, while epigenetics, lifestyle, and neurochemistry decide which switches actually get turned on—impacting everything from inflammation and gut issues to cognitive decline.

We also touch on how AI is now helping doctors interpret this data, moving from our current “sick care” model to something closer to true preventive healthcare. Len shares examples like the APOE4 gene and Alzheimer’s risk, cortisol’s impact on pain and gut health, and how simple choices around food, supplementation, and therapies can help keep your body closer to balance. This first part ends with a teaser into Len’s personal story—immigrating from Lithuania, getting labeled with ADD, discovering cannabis, and eventually building EndoDNA as a bridge between plant medicine and precision genetics.

Chapters:

• 00:21 Introduction to Our Biology
• 02:51 The Role of Lifestyle and Environment
• 09:15 Understanding Genetic Predispositions
• 10:24 Health and DNA: Prevention Strategies
• 18:29 Len's Journey to Genetics
• 26:13 The Intersection of Cannabis and Genetics
• 30:26 Conclusion and Next Steps

Guest: Len May, EndoDNA

• Website: https://shop.endodna.com
• Website: https://www.lenmaycoaching.com/
• LinkedIn: https://www.linkedin.com/in/lenmay

Companies / Vendors / Products Mentioned

• 23andMe: https://www.23andme.com
• Ancestry.com: https://www.ancestry.com
• Tower Records: https://www.towerrecords.com
• Rand McNally: https://www.randmcnally.com
• Heritage Cannabis Holdings: https://heritagecann.com

=== About the Unhealthy Podcast

Hosted by Marvin Bee (Uncle Marv), the Unhealthy Podcast dives into real conversations about health, wellness, and everyday habits that impact how we live, work, and age. From nutrition myths to stress management and tech-life balance, Uncle Marv brings humor, insight, and honesty to every episode.

• Visit our website: https://www.unhealthypodcast.com/ 
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