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Amber Salzman: Epigenetic Editing Aims to Refine Personalized Genetic Medicine
Amber Salzman: Epigenetic Editing Aims to Refine Personalized Genetic Medicine

Episode 22

With recent safety setbacks in gene therapy underscoring the risks of genetic medicine, Amber Salzman, PhD, is charting a different course. After 25 …

1 year, 2 months ago

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Mike Previte: Predicting Biology with Spatiotemporal Multiomics
Mike Previte: Predicting Biology with Spatiotemporal Multiomics

Episode 21

Think Good Will Hunting—but in biology. Mike Previte, PhD, once at Illumina and now CTO and co-founder of Element Biosciences, is building tools to m…

1 year, 2 months ago

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Hervé Affagard: Creating Microbiomes to Fight Cancer, ALS, and More
Hervé Affagard: Creating Microbiomes to Fight Cancer, ALS, and More

Episode 20

Hervé Affagard, CEO and co-founder of MaaT Pharma, traded industrial engineering for medicine after cancer struck his family. Now, he’s pioneering mi…

1 year, 3 months ago

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Michelle Werner: Engineered tRNAs Offer Universal Solutions to Stop Codon Diseases
Michelle Werner: Engineered tRNAs Offer Universal Solutions to Stop Codon Diseases

Episode 19

When Michelle Werner, PhD, learned her son Caffrey had Duchenne muscular dystrophy, she left big pharma to lead Alltrna—a Flagship Pioneering company…

1 year, 3 months ago

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Cassie Hajek: Population Genomic Screens Need More Than Pathogenic Variants
Cassie Hajek: Population Genomic Screens Need More Than Pathogenic Variants

Episode 18

Public health is greatly benefiting from population genomics screening, as it provides patients with risk education and treatment for symptoms of lif…

1 year, 4 months ago

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Patrick Hsu, Serge Saxonov, and Gilad Almogy: Creating the Virtual Cell
Patrick Hsu, Serge Saxonov, and Gilad Almogy: Creating the Virtual Cell

Episode 17

Three biotech trailblazers—Patrick Hsu (co-founder of the Arc Institute), Serge Saxonov (co-founder and CEO of 10x Genomics), and Gilad Almogy (co-fo…

1 year, 4 months ago

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Kate Sasser: How Lab-in-the-loop Turns Patient Data Into Patient Care
Kate Sasser: How Lab-in-the-loop Turns Patient Data Into Patient Care

Episode 16

For years, Tempus operated in mystery—its website sparse on details while headlines announced massive funding and high-profile partnerships. The clai…

1 year, 5 months ago

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Kian Sadeghi: Is Personalized Genomics Undergoing a Direct-to-Consumer Renaissance?
Kian Sadeghi: Is Personalized Genomics Undergoing a Direct-to-Consumer Renaissance?

Episode 15

At just 25, UPenn dropout Kian Sadeghi is betting big on personalized genomics. As founder of Nucleus Genomics, he’s offering affordable whole-genome…

1 year, 5 months ago

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Carlos D. Bustamante: Latin American Diversity’s Genetic Potential
Carlos D. Bustamante: Latin American Diversity’s Genetic Potential

Episode 14

Imagine a future where your ancestry not only tells a story about your past but also holds the key to your health. That's the vision drives Carlos D.…

1 year, 6 months ago

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Josh Denny: The Future of Precision Public Health
Josh Denny: The Future of Precision Public Health

Episode 13

Josh Denny, MD, turned a family tragedy with cystic fibrosis into a lifelong mission to transform medicine. Now CEO of the NIH’s All of Us Research P…

1 year, 6 months ago

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