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221: From 2D Cultures to Advanced 3D Cell Models for Preclinical Research with Catarina Brito - Part 1

Episode 221

What if the failure rate in clinical trials isn't about picking the wrong drug candidates—but about testing them in the wrong models?

When you move ce…

4 months, 4 weeks ago

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220: From 10,000 Structures to 1.8 Billion Interactions: Breaking the Data Bottleneck to Engineer Efficacious Therapeutics with Troy Lionberger - Part 2

Episode 220

The biotech industry stands on the verge of a radical transformation thanks to artificial intelligence (AI) and machine learning (ML). But even the m…

5 months ago

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219: From 10,000 Structures to 1.8 Billion Interactions: Breaking the Data Bottleneck to Engineer Efficacious Therapeutics with Troy Lionberger - Part 1

Episode 219

Antibody therapeutics have transformed modern medicine, but for many scientists, developing new candidates still feels like searching for a needle in…

5 months ago

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218: Silkworm Biomanufacturing: From Ancient Silk Production to Phase I Vaccine Trials with Masafumi Osawa - Part 2

Episode 218

For generations, silkworm pupae were discarded as waste from silk production. Now, KAICO is proving these organisms can function as highly efficient …

5 months, 1 week ago

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217: Silkworm Biomanufacturing: From Ancient Silk Production to Phase I Vaccine Trials with Masafumi Osawa - Part 1

Episode 217

For over 4,000 years, silkworms have connected civilizations through ancient trade routes. Now, KAICO Ltd., a Japanese biotech spin-off from Kyushu U…

5 months, 1 week ago

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216: From Data Silos to Autonomous Biomanufacturing: Digital Twins and AI-Driven Scale-Up with Ilya Burkov - Part 2

Episode 216

Biomanufacturing has always dealt with the challenge of turning vast, complex datasets and intricate production steps into life-changing therapies. B…

5 months, 4 weeks ago

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215: From Data Silos to Autonomous Biomanufacturing: Digital Twins and AI-Driven Scale-Up with Ilya Burkov - Part 1

Episode 215

Across biotech labs, researchers swim in oceans of process data: sensor streams, run records, engineering logs, and still, crucial decisions get stuc…

6 months ago

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214: From Developability to Formulation: How In Silico Methods Predict Stability Issues Before the Lab with Giuseppe Licari - Part 2

Episode 214

Computational methods can predict stability issues before the lab. But how do you actually implement these approaches in your formulation workflow? F…

6 months ago

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213: From Developability to Formulation: How In Silico Methods Predict Stability Issues Before the Lab with Giuseppe Licari - Part 1

Episode 213

What if you could predict formulation failures before ever touching a pipette? Computational approaches are revolutionizing biologics development, re…

6 months, 1 week ago

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212: When the Innovator Becomes the Patient: Manufacturing Reality vs. Patient Urgency with Jesús Zurdo - Part 2

Episode 212

What happens when cell therapy innovation meets real patient urgency? In this conversation, the barriers between scientist and patient all but vanish…

6 months, 1 week ago

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