Podcast Episodes
Back to SearchAUD Medications and Hepatic Safety
In this episode, we explore how liver status shapes medication choice for alcohol use disorder. Dr. Kevin Sevarino breaks down a practical algorithm …
1 month, 2 weeks ago
GLP-1 Agonists in Serious Mental Illness: Current Evidence
In this episode, we explore whether GLP-1 agonists like semaglutide can tackle the metabolic toll of antipsychotics in schizophrenia. Can a drug famo…
1 month, 3 weeks ago
Gabapentin, Topiramate & Baclofen in AUD
In this episode, we explore three off-label but evidence-supported medications — gabapentin, topiramate, and baclofen — for alcohol use disorder, exa…
1 month, 4 weeks ago
Deprescribing Benzodiazepines: When Tapering Might Do More Harm Than Good
In this episode, we explore the nuanced landscape of benzodiazepine tapering, guided by a major 2024 joint clinical practice guideline. Are we traini…
2 months ago
Disulfiram Unpacked: Efficacy, Risks, and Liver Safety
In this episode, we explore disulfiram (Antabuse), one of the oldest FDA-approved treatments for alcohol use disorder. Dr. Kevin Sevarino breaks down…
2 months, 1 week ago
GLP-1s and Lithium: What Clinicians Need to Know
In this episode, we explore a surprising drug interaction that every lithium-prescribing clinician should know about: can semaglutide, the widely use…
2 months, 2 weeks ago
Naltrexone for Alcohol Use Disorder: What You Should Know
In this episode, we explore how naltrexone — the most widely used medication for alcohol use disorder in the US — works, how to dose it safely, and w…
2 months, 2 weeks ago
The OPTIMUM Trial: A Roadmap for Treatment-Resistant Depression in Late Life
In this episode, we explore the OPTIMUM trial, a landmark study examining how to treat older adults with treatment-resistant depression when antidepr…
2 months, 3 weeks ago
Difficult-to-Treat Depression: First, Second, and Third-Line Strategies
In this episode, we explore what to do when antidepressants aren't working. How do you systematically approach a patient who isn't getting better — a…
2 months, 4 weeks ago
Is High-Dose Olanzapine A Clozapine Alternative?
In this episode, we explore whether high-dose olanzapine — beyond the FDA-approved 20 mg ceiling — can be a viable strategy for patients with treatme…
3 months ago