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Rough draft of Omicron origins

Episode 861

Nels joins TWiV to discuss hypotheses for the origins of Omicron, including that it came from mice or arose during chronic infection of an immunocomp…

3 years, 11 months ago

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Evading a Toll on the road to RNA vaccines

Episode 860

TWiV reviews a seminal paper showing that chemically modified bases in RNAs suppress recognition by Toll-like receptors, a finding that that was esse…

3 years, 11 months ago

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COVID-19 clinical update #99 with Dr. Daniel Griffin

Episode 859

In COVID-19 clinical update #99, Daniel Griffin discusses Omicron disease severity, neurologic manifestations in children, testing outcomes during mu…

3 years, 11 months ago

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The vax of life with John Mascola

Episode 858

John Mascola joins TWiV to discuss the history and mission of the NIH Vaccine Research Center, how it prepared for devising pandemic vaccines, and de…

3 years, 11 months ago

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Not just antibody, Jon Yewdell

Episode 857

Jon Yewdell returns to TWiV to discuss how antibodies are made, vaccination against SARS-CoV-2, antigenic variation of the virus, booster shots, and …

3 years, 11 months ago

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COVID-19 clinical update #98 with Dr. Daniel Griffin

Episode 856

In COVID-19 clinical update #98, Daniel Griffin reviews COVID-19 in South Africa, recognition of Omicron by ancestral T cells, booster effectiveness …

3 years, 11 months ago

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T time with Alessandro Sette

Episode 855

Alessandro Sette returns to TWiV to discuss the observation that SARS-CoV-2 vaccination induces T cells that are able to cross-recognize variants Alp…

3 years, 11 months ago

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Omicron is evasive

Episode 854

TWiV reviews findings that increased fitness of the Omicron variant is due to immune evasion, not an increase in intrinsic transmissibility, and dete…

3 years, 11 months ago

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COVID-19 clinical update #97 with Dr. Daniel Griffin

Episode 853

In COVID-19 clinical update #97, Daniel Griffin covers immunity after infection recognized by CDC, outcomes before and after Omicron, infectious vira…

4 years ago

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Tree man syndrome

Episode 852

A TWiV threesome explains the observation that humans with inherited T cell CD28 deficiency are susceptible to severe warts driven by human papilloma…

4 years ago

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