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Episode 519: What is the Appropriate Approach to Adjuvant Therapy for UTUC?
Episode 519: What is the Appropriate Approach to Adjuvant Therapy for UTUC?

Shilpa Gupta joins us to discuss an X poll revealing equipoise about treatment approaches to resected high-risk upper tract urothelial cancer (UTUC).

3 weeks ago

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Episode 518: PSMAddition in Clinical Practice
Episode 518: PSMAddition in Clinical Practice

Rob Dreicer joins the show to discuss the FDA approval of Lutetium Lu 177 in the mHSPC space and how to contextualize the benefit/risk

4 weeks ago

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Episode 517: Casdatifan Clinical Data in RCC and Translational Correlates
Episode 517: Casdatifan Clinical Data in RCC and Translational Correlates

Toni Choueiri joins Brian and Tom to discuss a recent Nature paper regarding the novel HIF inhibitor, casdatifan, and biomarkers of response.

1 month, 3 weeks ago

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Episode 516: The Influence of Hypoxia on Response and Resistance in RCC
Episode 516: The Influence of Hypoxia on Response and Resistance in RCC

Ari Hakimi and Lyn Voung from MSKCC join Brian and Tom to discuss their recent Cancer Cell paper exploring the mechanistic impact of TKI-induced hypo…

2 months, 1 week ago

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Episode 515: PROTEUS - A Reflection on the Data and Controversies with Neha Vapiwala
Episode 515: PROTEUS - A Reflection on the Data and Controversies with Neha Vapiwala

Brian and Tom invite Neha Vapiwala, a Radiation Oncologist, to discuss areas of consensus and controversy from the PROTEUS trial of ADT +/- apalutami…

2 months, 3 weeks ago

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Episode 514: Artificial Intelligence in Cancer Drug Development
Episode 514: Artificial Intelligence in Cancer Drug Development

Travis Zack, CMO of Open Evidence, joins Brian and Tom to discuss the emergence of AI across the spectrum on cancer, drug development and application…

3 months ago

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Episode 513: Trials and Tribulations of Investigator-initiated Research
Episode 513: Trials and Tribulations of Investigator-initiated Research

Bishoy Faltas joins Brian and Tom to discuss his IIT in bladder cancer. The intended discussion of the trials turned into an insightful discussion on…

3 months, 1 week ago

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Episode 512: ENZA-P Nature Medicine translational data
Episode 512: ENZA-P Nature Medicine translational data

In our final episode recorded at APCCC, Louise Emmett joins us to discuss clinical results and mechanisms of PSMA upregulation by enzalutamide.

3 months, 2 weeks ago

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Episode 510: ADCs in Prostate Cancer
Episode 510: ADCs in Prostate Cancer

Tanya Dorff joins Tom and Brian to discuss her ASCO 2026 data on a novel dual targeting ADC in prostate cancer. The broader scope of ADC development …

4 months, 1 week ago

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Episode 509: ASCO 2026 Review
Episode 509: ASCO 2026 Review

This comprehensive podcast covers the latest advances in prostate, bladder, and kidney cancers from ASCO 2026, including new therapies, trial data, a…

4 months, 2 weeks ago

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