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NSAIDs, Part 3: The rise, fall and rise again of COX-2 inhibition
Season 1 Episode 87
In the third episode of the NSAIDs saga, we focus on COX-2 inhibition! Did the hopes and dreams of selective COX-2 inhibition pan out? What can the rise and fall of VIOXX teach us about physiology?
…Published on 1 year ago
NSAIDs, Part 2: The Dawn of the Anti-Inflammatories
Season 1 Episode 86
In this episode, we dive into the story of aspirin and the development of ibuprofen, ending with the experiments that showed the mechanism of how aspirin actually works.
Intro 0:12 Review of part 1 …Published on 1 year, 2 months ago
The Discovery of Non-Steroidal Anti-inflammatory Drugs (NSAIDs), Part 1
Season 1 Episode 85
Humans have had an insatiable appetite for inhibiting production of prostaglandins for centuries! This series delves into the history of aspirin and NSAIDs, looking at the understanding of the prosta…
Published on 1 year, 4 months ago
Urticarial Vasculitis, Part 2: Walking the Balance Beam of Allergy and Rheumatology
Season 1 Episode 84
This episode digs into the pathophysiology of urticaria vasculitis from anti-C1q to the story of bradykinin.
· Intro 0:11
· In this episode 0:22
· Review of episode 83 1:23
· …
Published on 1 year, 5 months ago
Urticarial Vasculitis: Attack of the Nettles, Part 1
Season 1 Episode 83
Is it an allergy or an autoimmune vasculitis, or a little of both? Find out the story of urticarial vasculitis, how this disease was recognized and eventually sorted out from other types of urticaria…
Published on 1 year, 6 months ago
COVID-19, long COVID and the rheumatologist with Leonard Calabrese, DO
Season 1 Episode 82
What should rheumatologists know about what we've learned about COVID-19 and long COVID in 2023? Hosted by Dr. Leonard Calabrese.
· Intro 0:11
· In this episode 0:21
· 2023: curr…
Published on 1 year, 8 months ago
The Story of the Flu Vaccine
Season 1 Episode 81
It's that time of year again, everyone rolling up their sleeves to get a flu shot. This episode dives into the history of the struggles pinning down the causative agent of flu and the journey to the …
Published on 1 year, 9 months ago
It's in the Air: Silica exposure and the risk of autoimmunity, Part 4
Season 1 Episode 80
What is silica? How does it impact your risk of developing autoimmunity if you inhale it, inject it or even snort it up your nose? Listen and find out!
· Intro 0:12
· In the previous ep…
Published on 1 year, 10 months ago
The Lupus Gradient, Part 3
Season 1 Episode 79
In this episode, we dig through the data of lupus in Africa and speak with experts on the Lupus Gradient, the impact of malaria and what we can learn from it all.
· Intro 0:12
· In the …
Published on 1 year, 10 months ago
The Geography of Autoimmunity, Part 2
Season 1 Episode 78
This episode delves into what we can learn about the impact of the environment on autoimmunity, digging into how rates of autoimmunity can vary drastically in different parts of the world.
· I…
Published on 2 years, 1 month ago