Episode Details

Dermatologist Dr. Dray reviews the REMEDY 15% Azelaic Acid Complex Advanced Clarifying Serum, a $25 skincare serum marketed as containing a 15% azelaic acid complex. But there is an important distinction: this is not a 15% azelaic acid serum.
The formula contains 10% azelaic acid plus 5% potassium azeloyl diglycinate, also known as azeloglycine. Dr. Dray breaks down what is known about these ingredients, how potassium azeloyl diglycinate compares with azelaic acid, and whether this combination offers meaningful benefits over a traditional 10% azelaic acid product.
The video also covers the evidence for azelaic acid in acne, rosacea, and hyperpigmentation, the limited clinical evidence for potassium azeloyl diglycinate, and the other ingredients in the formula, including niacinamide, beta glucan, vitamin B12, centella asiatica, licorice root, and green tea extract.
Dr. Dray also shares her personal experience using the REMEDY serum. After a couple of weeks, she developed eyelid dryness and facial itching and discontinued the product. She notes that this is her individual experience and does not mean everyone will experience irritation.
The video also compares the REMEDY serum with the Anua 10% Azelaic Acid Serum, which Dr. Dray personally uses and repurchases. The two products have a similar overall concept and price range, but the Anua serum does not contain potassium azeloyl diglycinate or vitamin B12.
Most importantly, Dr. Dray explains why “15% azelaic acid complex” does not mean 15% azelaic acid, and why consumers should not assume that 5% potassium azeloyl diglycinate is equivalent to an additional 5% azelaic acid.
She also discusses why she would like to see prescription-strength azelaic acid become available over the counter in the United States, given its versatility in dermatology and established history of use.

Products Mentioned
Remedy 15% Azelaic Acid Complex Advanced Clarifying Serum https://amzlink.to/az0M7w6trRrcB
Anua Azelaic Acid 10 Serum https://amzlink.to/az0DaPVjUyYmq

Timestamps
0:00 REMEDY 15% Azelaic Acid Complex Introduction
0:35 What Does 10% Azelaic Acid Actually Do?
2:37 Potassium Azeloyl Diglycinate Explained
5:54 Niacinamide, Beta Glucan, Vitamin B12 and Botanicals
7:12 Dr. Dray's Experience With the Serum
8:23 Is the $25 Price Worth It?
9:35 REMEDY vs. Anua 10% Azelaic Acid
11:27 Final Thoughts

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