Episode Details

About 1 million Americans are living with Parkinson's disease, and only 4% are diagnosed before age 50. Isaac S. — Army veteran, former Division I linebacker, father of four, and husband to past guest Karli S. — is one of them. Diagnosed at 34, Isaac joins Dr. Kylie Burton and Jessica Briecke to walk through his path to diagnosis, what daily life with early-onset Parkinson's actually looks like, and how he's built a personal regimen — combining prescribed medication, exercise, and peptides — to stay as functional as possible.

Isaac describes the early, easy-to-dismiss symptoms (a weakening grip, subtle uneasiness) that were initially written off as stress, and the second opinion — pushed by his wife — that led to a DAT scan and diagnosis. He explains the basics of Parkinson's in plain terms: a decline in dopamine production that disrupts the brain-body signal for smooth movement, and the difference between bradykinesia (slowed movement) and dyskinesia (tremor-like breaks in movement). He's candid about the frustration of losing fine motor control for everyday tasks like brushing his teeth or changing the baby's diaper.

The conversation then turns to his personal management approach: prescribed medications (carbidopa-levodopa and selegiline), Botox for foot muscle control, daily exercise, and a peptide stack that includes microdosed tirzepatide, NAD+, glutathione, and MOTS-C. The hosts are careful to frame all of this as Isaac's individual experience and combination of care, not a treatment protocol for Parkinson's, and the episode closes with a conversation about the financial side of the peptide industry and the hosts' peptide provider network for healthcare professionals.

What You'll Learn

• Parkinson's disease basics, explained in plain terms: dopamine's role in movement, and the difference between bradykinesia (slowed movement) and dyskinesia (tremor-like breaks in movement)
• Isaac's path to diagnosis: early symptoms dismissed as stress, a second opinion, and the DAT scan that confirmed it
• What daily life with early-onset Parkinson's looks like, including the frustration of losing fine motor control for routine tasks
• Isaac's prescribed medical treatment may surprise you
• Why exercise — specifically a mix of intense cardio and weight training — is one of the most impactful tools for managing Parkinson's symptoms
• Isaac's personal peptide regimen alongside his prescribed care: microdosed tirzepatide (for inflammation), NAD+, glutathione, and MOTS-C, and what he noticed (and didn't) with each
• The importance of building a peptide stack with individualized guidance, since what worked for Isaac didn't work the same way for everyone
• The financial side of the story: how the peptide business helped stabilize the family's finances after Isaac's military salary alone couldn't sustain their mortgage

Find Isaac: Instagram @isaac_sine 

Find his wife Karli: Instagram @karli__sine

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Where do you start with peptide therapy? What do you add next? If you're a go-getter, check out Dr. Kylie's new program AMPLIFY. You'll find it on the homepage of her website: drkylieburton.com

Ready to explore peptide therapy for yourself? Join through Jessica's platform at B2BwithJess.com/peptides or through Dr. Kylie's platform at drkylieburton.com/shop. 

Want to offer peptide therapy in your business? Whether you're adding it to your existing practice or building something new, learn how to get started—and how we'll mentor you along the way—at drkylie