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Your Brain on Grief: Why Loss Rewires You (And How to Heal)
Published 13 hours ago
Description
Your body knows the difference between grief and sadness. When someone you love dies, your brain literally rewires itself, firing the same neural pathways as physical injury. That crushing feeling in your chest? It's not just a metaphor.
Dr. Mary-Frances O'Connor has spent two decades studying what grief actually does to your brain. Her research reveals why you can't think straight after loss, why your body feels broken, and most importantly, how to work with your brain instead of against it during the hardest moments of your life.
What you'll discover:
• Why grief triggers physical pain in the same brain regions as a broken bone
• How your reward system keeps searching for the person who's gone, creating neurological loops
• Why 80% of grieving people can't sleep (and it's not what you think)
• The specific brain changes that make simple decisions feel impossible
Nina breaks down the neuroscience behind loss and shares practical strategies that actually align with how your grieving brain works. No platitudes, no timeline pressure. Just science-backed approaches that honor what your mind and body are going through.
Chapters:
00:00 The neuroscience of heartbreak
02:15 Why your brain keeps looking for them
04:30 Sleep, memory, and the grieving mind
06:45 When your prefrontal cortex goes offline
08:20 Working with your brain's grief response
10:00 Building resilience through understanding
This episode won't fix your grief, but it might help you understand why healing takes the time it takes. Your brain is doing exactly what it's supposed to do.
New episodes of Brainwaves drop every day with medical research you can actually use. Hit follow if you want Nina's take on the science behind how your body really works.
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