Episode Details

A scientific look at the most popular anti-aging drugs & supplements

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Animations: Even Topland @toplandmedia

References:
Metformin
https://www.tandfonline.com/doi/pdf/10.4161/CC.7.17.6625
https://www.nature.com/articles/ncomms3192
https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2021.718942/full

Diabetes Prevention Program:
https://pmc.ncbi.nlm.nih.gov/articles/PMC3135022/pdf/nihms299552.pdf

Metformin & exercise:
https://onlinelibrary.wiley.com/doi/full/10.1111/acel.12880

Metformin & testosterone:
https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2021.813067/full

Rapamycin & aging:
https://link.springer.com/content/pdf/10.1007/s11357-020-00274-1.pdf
https://pmc.ncbi.nlm.nih.gov/articles/PMC4397165/pdf/nihms669810.pdf

mTOR inhibition & immunity:
https://pubmed.ncbi.nlm.nih.gov/25540326/

NAD:
https://www.sciencedirect.com/science/article/pii/S053155652300030X

NMN / NR:
https://onlinelibrary.wiley.com/doi/full/10.1002/jcsm.13799

Niacin:
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2730481
https://www.sciencedirect.com/science/article/abs/pii/S0002934316310580

Psyllium:
https://pmc.ncbi.nlm.nih.gov/articles/PMC7652639/
https://www.sciencedirect.com/science/article/pii/S1756464623002852
https://www.sciencedirect.com/science/article/pii/S0002916523070107
https://www.sciencedirect.com/science/article/pii/S0002916523272354

Betaine:
https://journals.lww.com/nsca-jscr/fulltext/2017/08000/effects_of_betaine_supplementation_on_muscle.35.aspx
https://journals.lww.com/nsca-jscr/fulltext/2011/12000/The_Effects_of_Chronic_Betaine_Supplementation_on.31.aspx

Magnesium:
https://www.sciencedirect.com/science/article/abs/pii/S0021915011004734

Vitamin K2:
www.youtube.com/watch?v=nkPEfVzm6io
https://www.ahajournals.org/doi/pdf/10.1161/circulationaha.121.057008