Episode Details

Why do SIBO, Candida, and other gut infections sometimes return—even after treatment initially seems successful?

In this episode of The Histamine Well Podcast, Joanne explains how biofilms may contribute to persistent bacterial and fungal overgrowths. Biofilms are organised microbial communities surrounded by a protective matrix that can help microorganisms survive antimicrobial treatment and resist immune defences.

Joanne explores the role biofilms may play in recurring SIBO, Candida overgrowth, gut dysbiosis, chronic sinus infections and MARCoNS. She also explains how bacteria and fungi can communicate, share resources and coexist within mixed-species biofilms.

You’ll discover:

• What biofilms are and why microorganisms create them
• Why SIBO, Candida and gut infections may keep returning
• How biofilms can protect bacteria and fungi
• The connection between biofilms, chronic sinus infections and MARCoNS
• How Candida and Aspergillus form fungal biofilms
• The difference between mould, mycotoxins and biofilms
• What the biofilm matrix is made from
• How enzymes and N-acetylcysteine may support biofilm disruption
• Why biofilm support should be introduced gradually during antimicrobial treatment

If you’re dealing with recurring digestive symptoms or want to better understand persistent microbial overgrowths, this episode offers a clear and practical introduction to biofilms and their potential role in gut and sinus health.

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