Episode Details

A red flag next to your LDL number can feel alarming, but LDL is only one part of a much larger cardiovascular risk picture. In this episode of Metabolic Mind, cardiologist and lipidologist Dr. Bret Scher explains how to read a cholesterol panel with more context and less fear.

Dr. Scher walks through LDL, triglycerides, HDL, non-HDL cholesterol, ApoB, Lp(a), and the triglyceride-to-HDL ratio. He also explains how the 2026 cholesterol guidelines use the PREVENT risk calculator, where LDL targets currently stand, and why individual risk factors, metabolic health, family history, and direct measures of vascular disease can change the conversation.

He covers:

• Why LDL should not be read in isolation
• What triglycerides and HDL can reveal about metabolic health
• Why Dr. Scher pays attention to the triglyceride-to-HDL ratio
• When LDL above 190 may raise concern for familial hypercholesterolemia
• Why Lp(a) should be measured at least once in adulthood
• How ApoB differs from LDL cholesterol
• What the PREVENT risk calculator includes
• How coronary calcium scans and CT angiograms act as tools that may help refine risk
• Why LDL targets vary by risk category
• Why metabolic health, insulin resistance, and individual preferences and priorities should be part of the discussion

A cholesterol panel can start a thoughtful conversation with your healthcare provider. One number rarely tells the whole story, and better decisions come from looking at the full cardiometabolic picture.

📘 Download Making Sense of Your Cholesterol, our free visual guide to understanding your lipid panel and preparing questions for your clinician: https://metmind.co/cholesterol-listeners

🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.

🎙️ Take the Metabolic Mind Podcast Listener Survey for a chance to win! We’d love your feedback on what you’re enjoying, what you’d like to hear more of, and how we can make the podcast even more helpful. Complete the quick survey by September 15 for a chance to win a Metabolic Mind giveaway bundle featuring a Keto-Mojo meter, books from Dr. Chris Palmer and Dr. Georgia Ede, Metabolic Mind swag, and more. Winners will be notified September 18. Take the survey here: https://metmind.co/survey-listeners

No purchase necessary. Open to U.S. residents and international participants 18+. Ends 9/15/26 at 11:59 PM PT. Void where prohibited.

#MetabolicMind #KetogenicTherapy #Cholesterol #HeartHealth

Expert Featured:

Bret Scher, MD - Baszucki Group Medical Director & Host of the Metabolic Mind Podcast

• https://www.linkedin.com/in/bret-scher-08baaa102/
• https://www.instagram.com/drscher858/?hl=en
• https://x.com/bschermd

Free CME Clinician Trainings:

Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.

Our courses have been made FREE by grants f