Episode Details
Back to Episodes
APOE4 Shrinks Brains Before Symptoms | Health and Fitness News
Description
Scientists have uncovered how the APOE4 gene, a top Alzheimer’s risk factor, sabotages brain health years before symptoms strike—by turbocharging a protein called Nell2 that shrinks neurons and overexcites memory circuits in young mice. This early hyperactivity predicts future cognitive decline, but here’s the kicker: lowering Nell2 in adult mice reversed damage, restoring normal neuron size and activity. This breakthrough identifies Nell2 as a promising new drug target, offering hope to halt Alzheimer’s progression in high-risk individuals long before it’s too late.
Listen in comfort:
Get a discount on a Soli Pillow: http://solipillow.com/discount/dnn.
Advertise on DNN:
advertise@thednn.ai
This is an automated, high-level news summary based on public reporting.
Report issues to feedback@thednn.ai.
View sources & latest updates:
https://sources.thednn.ai/fe1aa06852e81798