Episode Details

The drugs were killing people. In April 1989 the safety board stopped the Cardiac Arrhythmia Suppression Trial. Testing an assumption exposes you to temporary downside to discover what actually works.

Featuring: Annie Duke, Nassim Nicholas Taleb, Stewart Brand, Lewis Carroll, Orville Wright, Otto Lilienthal, Ignaz Semmelweis, Roberto Goizueta

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Chapters:

(00:00) The Cardiac Arrhythmia Suppression Trial gets halted
(00:44) A high-converting email page and the cost of split tests
(01:27) Why leaving a working system alone feels safer
(01:38) Leigh Van Valen and the Red Queen principle
(02:24) Most experiments pay nothing

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