Episode Details
Back to EpisodesCan Your Natural Hunger Hormones Help After GLP-1s? w/ Sarah Kennedy
Description
What happens to hunger and food noise when someone lowers their GLP-1 dose or stops taking the medication?
In this episode, Ana Reisdorf talks with Calocurb founder and CEO Sarah Kennedy about a unique supplement designed to support appetite regulation by stimulating the body’s natural satiety hormones.
Sarah walks through the reported results of a 24-week clinical trial involving 150 adults. She says the Calocurb group averaged 5.4% weight loss, reduced fat and visceral fat, and maintained skeletal muscle. Ana asks how the study was conducted, how hunger and cravings were measured, what side effects users may experience, and what evidence currently exists for using Calocurb alongside or after GLP-1 medication.
**IN THIS EPISODE**
- How Calocurb was developed from a New Zealand research initiative
- What the new 24-week clinical trial measured and reported
- How researchers measured hunger and food cravings
- The roles of CCK, GLP-1, and PYY in appetite regulation
- When and how Calocurb is designed to be taken
- Possible digestive side effects and the onboarding process
- Where Calocurb might fit alongside or after GLP-1 medication
- What research is still needed for people reducing or stopping GLP-1s
- Potential future studies involving postmenopausal women and adolescents
- Why Sarah describes Calocurb as a tool rather than a magic pill
**ABOUT THE GUEST**
Sarah Kennedy is the founder and CEO of Calocurb, a veterinarian by training, and an experienced nutrition and health-industry executive. During more than 20 years in dietary and animal nutrition, she led Healtheries/Vitaco New Zealand and held senior international and nutrition leadership positions at Fonterra. She is also an MIT Sloan Fellow in Global Leadership and Innovation and has served on the boards of government, private, philanthropic, and publicly listed organizations.
**CONNECT WITH SARAH AND CALOCURB**
Website:
https://calocurb.com
Instagram:
https://www.instagram.com/calocurb
YouTube:
https://www.youtube.com/@calocurb
**SPONSORS**
Johnson Fitness and Wellness offers home fitness equipment, expert guidance, delivery, and professional installation. Shop online and use code GLP1Hub5 for an exclusive offer:
https://www.johnsonfitness.com
Tyde Wellness provides clinician-guided GLP-1 care, nutrition support, hormone therapy, and longevity services. Use code GLP1Hub50 for $50 off your first month:
https://tydewellness.com/GLP1Hub
**CHAPTERS**
00:00 Why reducing calories can increase hunger
00:25 What happens when GLP-1 treatment changes?
01:34 Meet Sarah Kennedy
02:07 How CaloCurb was developed
05:20 What the 24-week trial reported
07:30 Trial design and lifestyle support
09:09 How hunger and cravings were measured
11:16 CCK, GLP-1, and PYY explained
13:16 When and how CaloCurb is used
16:47 Could it fit alongside or after GLP-1s?
19:02 Appetite regulation and weight maintenance
22:12 Side effects and the onboarding process
24:39 Combining CaloCurb with GLP-1 medication
26:33 Future studies and unanswered questions
29:48 Studying appetite support in adolescents
31:11 A tool, not a magic pill
33:59 Where to learn more
MORE FROM GLP-1 HUB
📬 Get The Steady State, Ana's weekly newsletter with GLP-1 guidance from a dietitian who's on one: http://join.glp-1hub.com
🎙 Subscribe wherever you listen to podcasts, and if this episode helped, leave a quick review on Apple Podcasts or Spotify - it's the single best way to help more peo