Episode Details
Back to Episodes
Gilbert's Syndrome to Rare IEMs: A Metabolic Spectrum Tour
Episode 4535
Published 1 week, 5 days ago
Description
A routine blood panel reveals Gilbert's syndrome, and suddenly the vast landscape of inborn errors of metabolism opens up. From Archibald Garrod's 1902 discovery to modern gene therapy, we explore how these 1,450 conditions are classified, why methylation is so misunderstood, and why some are harmless while others are life-threatening. This episode maps the spectrum from benign lab curiosities to devastating infantile disorders.