Episode Details

Could a ketogenic diet and low-dose GLP-1 medications work better together? A new case series suggests they might, while highlighting a more personalized approach to metabolic health.

GLP-1 medications have transformed obesity treatment, but they aren't the only tool available. In this interview, Dr. Bret Scher speaks with physician assistant Bill Jensen about a newly published case series exploring the combination of a ketogenic diet and low-dose semaglutide. Together, they discuss how this approach may help preserve lean mass, improve insulin resistance, reduce side effects, and empower patients to take an active role in their health.

In this video:

• Why low-dose GLP-1s may complement a ketogenic diet
• The importance of preserving muscle during weight loss
• Which patients may benefit most from this approach
• Why this case series is hypothesis-generating, not definitive
• How lifestyle and medication can work together to improve metabolic health

This conversation examines how a more personalized approach to care could improve long-term health outcomes. Rather than asking whether medication or lifestyle is "better," it explores how combining the right tools for the right person may help improve body composition, support metabolic health, and empower patients to play an active role in their care.

💡 Not all ketogenic diets are the same. If you’re interested in learning more about what a well-formulated ketogenic diet looks like, check out our blog: Understanding the Well-Formulated Ketogenic Diet.

🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.

#MetabolicMind #KetogenicTherapy #GLP1

Expert Featured:

Bill Jenson PA-C, MMS

• https://www.summitfamilyhealth.org/dr-jensen
• https://www.linkedin.com/in/william-jensen-45027053/
• https://www.instagram.com/summitmetabolichealth/

Resources Mentioned:

Personalized Combination of a Ketogenic Diet and Low-Dose Semaglutide for Cardiometabolic Health: A Retrospective Case Series

• https://doi.org/10.3390/jpm16060313

Free CME Clinician Trainings:

Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.

Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits:

https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-yt

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