Episode Details

Microdosing GLP-1s is quickly becoming one of the most talked-about topics in obesity medicine, but can taking less actually produce better long-term results for some people?

In this episode, Dr. Karen Mann shares how personalized GLP-1 dosing, food noise, behavior change, and identity-based habits may be the missing pieces to sustainable weight management. We also discuss preserving muscle, optimizing protein intake, resistance training, menopause, hormone replacement therapy, and why lasting health depends on changing who you become—not just what you weigh.

#GLP1 #Microdosing #FoodNoise #WeightLoss

TIMESTAMPS

[00:00] Why discomfort is the key to lasting behavior change

[00:43] Welcome to The Optimized Woman

[01:15] Dr. Karen Mann's personal journey into obesity medicine

[02:51] Why weight management requires a personalized approach

[04:18] Why standard GLP-1 dosing isn't right for everyone

[08:08] Why behavior change matters more than motivation

[10:45] Finding your "why" and building identity-based habits

[14:56] Becoming the person you want to become

[16:32] Coaching, accountability and habit formation

[18:46] What microdosing GLP-1s actually means

[22:09] New oral GLP-1 medications explained

[26:15] Food noise, emotional eating and impulse control

[29:43] Ultra-processed foods and why we're still hungry

[34:16] Can you lose weight eating unhealthy foods?

[36:10] Protein, muscle loss and resistance training

[39:42] Why strength training becomes essential with age

[42:21] Hormone replacement therapy and healthy aging

[47:49] Self-talk, self-compassion and changing your mindset

[50:56] Redefining discomfort as an act of self-love

LET'S CONNECT

Guest: Dr. Karen Mann, MD

Instagram: https://www.instagram.com/drkarenmann/

Host: Orshi McNaughton

Podcast: https://optimized-women.captivate.fm/listen

Website: https://www.optimizedwomen.com/

YouTube: https://www.youtube.com/@optimizedwomen

Instagram: https://www.instagram.com/orshimcnaughton

Substack: https://substack.com/@orshimcnaughton