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Brain’s Hidden Gatekeeper Discovered | Health and Fitness News
Description
Scientists have discovered a hidden cellular structure called the membrane-associated periodic skeleton, or MPS, that acts as a gatekeeper for nutrient and molecule intake in brain cells. Previously thought to be just structural support, MPS now reveals itself as a dynamic regulator of endocytosis — crucial for learning and memory. When disrupted, it triggers a dangerous feedback loop: over-absorption weakens MPS, opening more entry points and accelerating the buildup of Alzheimer’s-linked proteins and toxic fragments. This breakthrough suggests MPS could be a new therapeutic target to slow or prevent neurodegenerative decline by stabilizing this cellular traffic cop.
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