Episode Details

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👉 MTHFR, Methylation & Menopause: The Hidden Link Between Genes, Detox, and Fat Loss | MMP Ep. 246: https://youtu.be/8ZBcydkp-HI

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Your anxiety, your severe PMS, your flat mood in perimenopause — there is a gene that may be running all of it. In this episode of the Metabolism and Menopause Podcast, Stephanie Crassweller breaks down the COMT gene (catechol-O-methyltransferase) — one of the most clinically significant genetic factors for women's hormonal health, and one almost nobody is talking about.

You'll learn: what COMT does in the body, why its variants — Slow, Intermediate, and Fast — produce completely opposite symptoms, how estrogen directly modulates COMT activity across the cycle and into perimenopause, and what targeted nutritional and lifestyle support looks like for each type. Includes a self-identification checklist, DUTCH test guidance, and practical protocols you can start today.

📖 My Book, Conquering Menopause, Preorder Link: https://www.barnesandnoble.com/w/conquering-menopause-stephanie-crassweller/1151129377?ean=9798895741719

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• Our Website: https://www.vitalityoet.com

• Email: stephanie@vitalityoet.com

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• All Resources: https://stan.store/vitalityoetstephanie

Medical Disclaimer: The information shared in this podcast is for educational and informational purposes only and is not intended to provide medical advice, diagnosis, or treatment. It should not be used as a substitute for advice from your physician or other qualified healthcare professional. Always consult with your healthcare provider before making changes to your diet, exercise, medications, supplements, or healthcare plan. Never disregard or delay seeking professional medical advice because of something you heard on this podcast.

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