Episode Details

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Today's topics:

AI spa-style body imaging - Midjourney teased a fast full-body ultrasound imaging concept and even a planned "scanner spa"—raising big questions about AI, regulation, and medical validation.

Cheap academic drug repurposing trials - A King’s College London study argues hospitals and universities quietly run low-cost late-stage drug repurposing trials, expanding affordable treatments after patents expire.

Local vs cloud AI reliability - A practitioner’s write-up contrasts local Qwen models with frontier cloud AI, emphasizing privacy wins but warning about hallucinations, looping, and lower trust for long agentic coding.

AI-assisted retro hardware emulation - A MAME developer used AI to accelerate debugging of Power Macintosh emulation, turning long-standing boot failures into measurable progress and highlighting AI’s role as an expert tool.

New version control for binaries - Epic released Lore, an open-source version control system aimed at huge repos with large binary assets—relevant to games, media, and any team fighting repo scale.

Reproducible WebAssembly security builds - The Anubis project detailed the messy reality of deterministic builds for WASM and JS fallbacks, a key requirement for auditable security tooling and supply-chain trust.

Varnish Cache becomes Vinyl Cache - The long-running community Varnish Cache project rebranded to Vinyl Cache, clarifying governance and avoiding confusion with a separate corporate-controlled code line using the old name.

AMD Ryzen memory encryption controversy - Reports suggest AMD’s TSME memory encryption can vanish on some consumer Ryzen systems after newer AGESA firmware, affecting physical-attack defenses and transparency for users.

-Study Finds Hospitals and Universities Can Repurpose Drugs in Late-Stage Trials at a Fraction of Industry Cost
-Midjourney Unveils Plan for 60-Second Ultrasound Body Scanner and Spa-Based Health Imaging
-DeepSeek Chat Site Displays Cookie Consent Notice
-Alex Ellis: Local Qwen Isn’t ‘Near Opus’—It’s Best for Private, Bounded Workflows
-AI-Assisted Debugging Unlocks Major MAME Progress on Power Macintosh Emulation
-Epic Games Open-Sources Lore Version Control Built for Large Binary Assets
-Anubis Vendors wasm2js After Reproducible Build Issues With WASM Toolchains
-Vinyl Cache Expl