Episode Details

A provocative look at how far “human maximization” could go—from psychedelics and GLP-1s to sex, sleep, hair growth, and longevity. In the original episode, Ross Douthat speaks with investor and entrepreneur Christian Angermayer, who has put over $100 million of his own money into psychedelics and is backing a future of medical enhancement, AI-driven abundance, and the Enhanced Games. This condensed version cuts the full conversation down from the original runtime to a quick listen, highlighting Angermayer’s case for psilocybin and 5-MeO-DMT in mental health, his personal routine with TRT and sleep aids, and his belief that optimizing health is not vanity but a path to better living. You’ll also hear the ethical debate around performance-enhancing drugs, the line between healing and enhancement, and what human enhancement might mean for medicine, technology, and aging. Listen now to get the key ideas in minutes.