Episode Details

Ivermectin, is a Food and Drug Administration (FDA)-approved antiparasitic drug, https://www.covid19treatmentguidelines.nih.gov/therapies/antiviral-therapy/ https://www.covid19treatmentguidelines.nih.gov/therapies/antiviral-therapy/ivermectin/ Direct from official FDA site used to treat several neglected tropical diseases, including onchocerciasis, helminthiases, and scabies. For these indications, ivermectin has been widely used and is generally well-tolerated Ivermectin is not approved by the FDA for the treatment of any viral infection. Proposed Mechanism of Action and Rationale for Use in Patients With COVID-19 (in vitro studies) suggest that ivermectin acts by, Inhibiting host importin nuclear transport proteins Interfere with SARS-CoV-2 spike protein attachment to the human cell membrane Some studies of ivermectin have also reported potential anti-inflammatory properties Shown to inhibit replication of SARS-CoV-2 in cell cultures COVID-19 medical misinformation policy https://support.google.com/youtube/answer/9891785 https://support.google.com/youtube/answer/11161123 If you're posting content Don't post content on YouTube if it includes any of the following: Treatment misinformation: Content that claims that there's a guaranteed cure for COVID-19 Content that recommends use of Ivermectin or Hydroxychloroquine for the treatment of COVID-19 Categorical claims that Ivermectin is an effective treatment for COVID-19 Claims that Ivermectin and Hydroxychloroquine are safe to use in the prevention of COVID-19 Other content that discourages people from consulting a medical professional or seeking medical advice Prevention misinformation: Content that promotes prevention methods that contradict local health authorities or the WHO. Claims that there is a guaranteed prevention method for COVID-19 Claims that any medication or vaccination is a guaranteed prevention method for COVID-19 Content that recommends use of Ivermectin or Hydroxychloroquine for the prevention of COVID-19 Claims that Ivermectin and Hydroxychloroquine are safe to use in the prevention of COVID-19 Monitoring, Adverse Effects, and Drug-Drug Interactions The FDA first issued a warning in April 2020 that ivermectin intended for use in animals should not be used to treat COVID-19 in humans. This warning was updated and reiterated in 2021. https://www.fda.gov/consumers/consumer-updates/why-you-should-not-use-ivermectin-treat-or-prevent-covid-19 FDA, Recommendation The Panel recommends against the use of ivermectin for the treatment of COVID-19, except in clinical trials The Panel will continue to review emerging data on ivermectin use, including the results from 2 large, ongoing randomized controlled trials. Clinical Trials Several clinical trials evaluating the use of ivermectin for the treatment of COVID-19 are currently underway or in development. Please see ClinicalTrials.gov for the latest information. Bangkok Egypt Malaysia Is this one of the two? https://www.principletrial.org/news/ivermectin-to-be-investigated-as-a-possible-treatment-for-covid-19-in-oxford2019s-principle-trial Ivermectin to be investigated in adults aged 18+ as a possible treatment for COVID-19 in the PRINCIPLE trial 23 June 2021 Time line https://www.principletrial.org/news/the-principle-trial-two-years-on

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