Episode Details

Fatty liver disease (MASLD) is a major cause of liver disease and even liver failure. But many are surprised to learn it’s not primarily a liver problem. Growing evidence suggests the root issue may be metabolic dysfunction affecting the entire body, and that perspective can drastically change how we approach treating and preventing it.

In this interview, Dr. Bret Scher sits down with Dr. Adam Wolfberg to discuss a newly published study in Hepatology examining how a ketogenic intervention may help prevent metabolic liver disease before it progresses.

The conversation explores MASLD (metabolic dysfunction-associated steatotic liver disease) and MASH (metabolic dysfunction-associated steatohepatitis), conditions that now affect millions of people and are closely linked to obesity, insulin resistance, and type 2 diabetes.

You’ll learn:

• Why metabolic diseases are deeply interconnected
• How ketogenic interventions may improve liver health
• What the new research found about preventing MASLD and MASH
• Why weight loss alone may not explain the benefits
• How lifestyle interventions compare to pharmaceutical approaches
• Why prevention is often overlooked in modern healthcare
• The broader connection between metabolic health and chronic disease

Dr. Wolfberg also explains why treating metabolic dysfunction as a whole-body condition, rather than a collection of separate diseases, may change the future of medicine.

🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.

#MetabolicMind #KetogenicTherapy #LiverDisease

Expert Featured:

Dr. Adam Wolfberg

• https://www.linkedin.com/in/adamwolfberg/
• https://x.com/AdamWolfberg

Resources Mentioned:

• https://www.virtahealth.com/
• https://www.linkedin.com/company/virta-health/
• https://www.instagram.com/virtahealth/

Free CME Clinician Trainings:

Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein, Dr. Mariela Glandt, Dr. Deanna Kelly, Dr. Julie Milder, Dr. Zoltan Sarnyai, and Dr. Bret Scher with more coming soon.

Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits: https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-yt

Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.

Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/