Episode Details

Hook: When estrogen shifts in midlife, your gut can become the central driver of aging and recovery. In this condensed version (original ≈75 minutes → 15 minutes), host Dhru Purohit and guest Cynthia Thurlow map how the microbiome—what Cynthia calls the ‘microgenderome’—reshapes immunity, brain health, bone density, mood, and weight during perimenopause and menopause. You’ll learn clear signs a gut imbalance may be masquerading as hormonal symptoms (bloating, skin rashes, brain fog), the harms of antibiotics and alcohol, and practical, research-backed levers: parasympathetic support, fiber-rich foods to boost butyrate, sleep, strength training, trauma work, and when to consider HRT or targeted supplements. Topics: gut health, microbiome, perimenopause, longevity, biohacking, sleep, nutrition. Listen now to get the key ideas in minutes.